Nitric oxide delivery system
First Claim
Patent Images
1. A method of delivering nitric oxide to a mammal comprising:
- disposing a cathode and an anode in a solution of a nitric oxide precursor;
applying a voltage across the cathode and anode to generate nitric oxide substantially devoid of nitrogen dioxide;
contacting a transport gas with the solution of nitric oxide precursor to form a therapeutic gas; and
transporting the therapeutic gas to a mammal.
6 Assignments
0 Petitions
Accused Products
Abstract
Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
-
Citations
37 Claims
-
1. A method of delivering nitric oxide to a mammal comprising:
-
disposing a cathode and an anode in a solution of a nitric oxide precursor;
applying a voltage across the cathode and anode to generate nitric oxide substantially devoid of nitrogen dioxide;
contacting a transport gas with the solution of nitric oxide precursor to form a therapeutic gas; and
transporting the therapeutic gas to a mammal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
-
-
19. A method of delivering nitric oxide from an electrochemical cell to a mammal comprising:
-
disposing a cathode and an anode in a solution of dilute nitric acid, the anode including copper;
applying a voltage across the cathode and the anode to generate nitric oxide substantially devoid of nitrogen dioxide;
contacting a transport gas through the solution of dilute nitric acid to form a therapeutic gas including the nitric oxide; and
transporting the therapeutic gas to the mammal. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 37)
-
- 30. A kit comprising a nitric oxide precursor and instructional material describing a method of generating a therapeutic gas and transporting the therapeutic gas, the therapeutic gas comprising nitric oxide and being substantially devoid of nitrogen dioxide.
Specification