Implantable device for access to a treatment site
First Claim
1. An implantable guide for facilitating repeated access to a treatment site in a subject, the guide comprising:
- a proximal end, a distal end, and a guide body, wherein the guide body defines a lumen extending from the guide proximal end to the guide distal end; and
a stable positioning element for stably positioning at least a portion of a drug delivery device within the guide.
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Accused Products
Abstract
The present invention provides an implantable guide for access to a treatment site. The implantable guide comprises a proximal end, a distal end, and a guide body defining a lumen, and can optionally comprise a stable positioning element for stably positioning a drug delivery device within the guide. The guide can be provided in connection with a drug delivery device. In use, the guide is implanted within a subject so as to provide a conduit through which a drug delivery device can be retrievably introduced to facilitate delivery of drug to a treatment site within a subject at a site distal to an accessible implantation site. The drug delivery device is then positioned within the guide lumen to provide for delivery of drug from the drug delivery to the desired treatment site.
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Citations
53 Claims
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1. An implantable guide for facilitating repeated access to a treatment site in a subject, the guide comprising:
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a proximal end, a distal end, and a guide body, wherein the guide body defines a lumen extending from the guide proximal end to the guide distal end; and
a stable positioning element for stably positioning at least a portion of a drug delivery device within the guide. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 50, 51, 52, 53)
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11. An implantable guide for facilitating repeated access to a treatment site in a subject, the guide comprising:
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a proximal end, a distal end, and a guide body, wherein the guide body defines a lumen extending from the guide proximal end to the guide distal end; and
a sealing element for providing a liquid-resistant seal with at least a portion of a drug delivery device positioned within the guide lumen. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A drug delivery device comprising:
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a drug release device comprising a reservoir, and an orifice defined by a distal portion of the drug release device;
a substantially hollow drug delivery catheter comprising a drug delivery catheter proximal end and a drug delivery catheter distal end, wherein the drug delivery catheter proximal end is coupled to the drug release device to provide a drug flow pathway from the reservoir, through the orifice, and through a lumen of the drug delivery catheter; and
a stable positioning element for stably positioning at least a portion of the drug delivery device within a guide. - View Dependent Claims (22, 23, 24, 25, 26)
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27. A drug delivery device comprising:
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a drug release device comprising a reservoir, and an orifice defined by a distal portion of the drug release device;
a substantially hollow drug delivery catheter comprising a drug delivery catheter proximal end and a drug delivery catheter distal end, wherein the drug delivery catheter proximal end is coupled to the drug release device to provide a drug flow pathway from the reservoir, through the orifice, and through a lumen of the drug delivery catheter; and
a sealing element for providing a liquid-resistant seal with a guide. - View Dependent Claims (28, 29, 30, 31, 32)
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33. A system for delivery of drug to a treatment site comprising:
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an implantable guide comprising a proximal end, a distal end, and a guide body, wherein the guide body defines a lumen extending from the guide proximal end to the guide distal end;
a drug delivery device, wherein at least a portion of the drug delivery device is removably and stably positioned within the guide lumen; and
a stable positioning element that stably and removably associates the guide with the drug delivery device;
wherein the drug delivery device is positioned for delivery of drug from a drug reservoir of the drug delivery device and through the distal end of the guide lumen to the treatment site. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42)
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43. A system for delivery of drug to a treatment site comprising:
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an implantable guide comprising a proximal end, a distal end, and a guide body, wherein the guide body defines a lumen extending from the guide proximal end to the guide distal end;
a drug delivery device, wherein at least a portion of the drug delivery device is removably and stably positioned within the guide lumen; and
a sealing element positioned between an inner wall of the guide lumen and an outer wall of the drug delivery device;
wherein the drug delivery device is positioned for delivery of drug from a drug reservoir of the drug delivery device and through the distal end of the guide lumen. - View Dependent Claims (44, 45, 46, 47, 48, 49)
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Specification