Apparatus and method for ventricular rate regularization with biventricular sensing

• US 20030069610A1
• Filed: 11/25/2002
• Published: 04/10/2003
• Est. Priority Date: 05/21/1999
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Spinelli, Julio C., Stahmann, Jeffrey E., Ding, Jiang, Kramer, Andrew P.
• Granted Patent: US 6,988,002 B2
• Time in Patent Office: Days
• US Class Current: 607/25
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy

Abstract

A method and system for operating a cardiac pacemaker which employs pacing therapy to regularize the ventricular rhythm together with biventricular sensing. Biventricular sensing allows the ventricular rate regularization to be accomplished with greater hemodynamic stability.

Claims

1. An implantable device, comprising:

ventricular sensing channels for sensing right and left ventricular depolarizations and generating ventricular sense signals in accordance therewith;

telemetry interface means for communicating information;

an exertion level sensor means for measuring exertion levels;

a ventricular pacing channel for pacing a ventricle; and

controller means for providing a ventricular pace delivered upon expiration of a ventricular escape interval without receiving a ventricular sense from either ventricular sensing channel, wherein the ventricular escape interval starts with either a ventricular pace or a ventricular sense, the reciprocal of the ventricular escape interval being the lower rate limit,

the controller means measuring an R-R interval associated with each ventricular sense, wherein an R-R interval is the time between a ventricular sense and the preceding ventricular sense or ventricular pace, the reciprocal of the R-R interval thus being the measured intrinsic ventricular rate, and

the controller means adjusting the ventricular escape interval in accordance with a measured R-R interval so that the lower rate limit adjusts in accordance with changes in the measured intrinsic ventricular rate,

wherein the controller means is coupled to the exertion level sensor means to implement rate-adaptive pacing and the controller means is connected to the telemetry interface means for communications by the implantable device.

2. The implantable device of claim 1, wherein the ventricular escape interval is adjusted to move toward the measured R-R interval multiplied by a scaling factor.

3. The implantable device of claim 2, wherein the ventricular escape interval is adjusted by computing a weighted average of the measured R-R interval multiplied by a scaling factor and the previous value of the ventricular escape interval.

4. The implantable device of claim 1, wherein the ventricular escape interval is adjusted in accordance with a measured R-R interval after each ventricular sense.

5. The implantable device of claim 1, wherein the controller means further adjusts the ventricular escape interval toward a value corresponding to a base lower rate limit after a ventricular pace.

6. The implantable device of claim 5, wherein the controller means further adjusts the ventricular escape interval after a ventricular pace by multiplying the escape interval by a decay coefficient.

7. The implantable device of claim 1, wherein the controller means further adjusts the ventricular escape interval by computing a weighted average of the measured R-R interval multiplied by a scaling factor and the previous value of the ventricular escape interval after each ventricular sense, and wherein the ventricular escape interval is adjusted by multiplying the escape interval by a decay coefficient after a ventricular pace.

8. The implantable device of claim 7, wherein the scaling factor is selected to be greater than one such that the lower rate limit is moved toward a fraction of the intrinsic ventricular rate after each ventricular sense.

9. The implantable device of claim 8, wherein the scaling factor is selected to be less than one such that the lower rate limit is moved toward a value that is above the intrinsic ventricular rate after each ventricular sense.

10. The implantable device of claim 1, further comprising a second ventricular pacing channel for pacing a second ventricle.

11. The implantable device of claim 1, wherein the exertion sensor means includes an accelerometer

12. The implantable device of claim 1, wherein the exertion sensor means includes a minute ventilation sensor.

13. The implantable device of claim 1, wherein the telemetry interface means includes means for transmitting data collected by the implantable device.

14. The implantable device of claim 1, wherein the telemetry interface means includes means for adjusting parameter settings.

15. The implantable device of claim 1, wherein the telemetry interface means includes means for changing pacing modes.

16. The implantable device of claim 1, wherein the implantable device implements a uni-ventricular pacing mode.

17. The implantable device of claim 1, wherein the implantable device implements a biventricular pacing mode.

18. The implantable device of claim 1, wherein the controller means is at least partially implemented with software.

19. The implantable device of claim 1, wherein the controller means is at least partially implemented with discrete components.

20. The implantable device of claim 1, further comprising a recursive digital filter.