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Compositions and methods for liquid metering in microchannels

  • US 20030070677A1
  • Filed: 07/23/2001
  • Published: 04/17/2003
  • Est. Priority Date: 07/24/2000
  • Status: Active Grant
First Claim
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1. A method, comprising the steps of:

  • (a) providing a device comprising i) a microdroplet transport channel, said channel having one or more hydrophobic regions; and

    ii) a gas port in fluidic communication with said channel; and

    (b) introducing a first volume liquid into said channel so as to create a liquid-containing channel and under conditions such that said first volume of liquid is confined by at least one of said hydrophobic regions so as to create a first terminus; and

    (c) introducing a volume of gas through said gas port into said liquid-containing channel under conditions such that said gas divides the liquid in said channel so as to create a second terminus, said first and second termini defining a second volume of liquid.

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