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Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices

  • US 20030073106A1
  • Filed: 05/31/2002
  • Published: 04/17/2003
  • Est. Priority Date: 12/08/1998
  • Status: Abandoned Application
First Claim
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1. A kit for the analysis of a sample containing a nucleic acid molecule comprising a target sequence, said kit comprising a matrix and at least one non-nucleotide probe having a probing nucleobase sequence that sequence specifically hybridizes, under suitable hybridization conditions, to at least a portion of the target sequence sought to be detected in said sample to thereby form a non-nucleotide probe/target sequence complex and wherein the backbone of the non-nucleotide probe or probes is sufficiently neutral or positively charged, under electrostatic binding conditions, that it exhibits little or no affinity for the matrix.

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