Novel human collagen proteins and polynucleotides encoding the same

• US 20030077820A1
• Filed: 08/14/2002
• Published: 04/24/2003
• Est. Priority Date: 08/14/2001
• Status: Abandoned Application

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Hu, Yi, Xie, Qiongshu, Yu, Xuanchuan (Sean)
• Application Number:
  US10/219,449
• Publication Number:
  US 20030077820A1
• Time in Patent Office: Days
• US Class Current: 435/325
• CPC Class Codes: C07K 14/78 Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated polynucleotide encoding an amino acid sequence drawn from the group consisting of SEQ ID NO:

2 and SEQ ID NO;

4.

2. An isolated cDNA molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

2; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

1 or the complement thereof.

3. An isolated recombinant expression vector comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

2.

6. A cell comprising the expression vector of claim 3.

4. A substantially isolated protein comprising the amino acid sequence shown in SEQ ID NO:

2.

5. An isolated recombinant expression vector comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

4.

7. A cell comprising the expression vector of claim 5.