Solid compositions exhibiting iron binding activity
First Claim
1. A solid porous composition, substantially insoluble in water, comprising at least 25% by weight of an oxidised cellulose and exhibiting a significant capacity to remove iron from an aqueous environment.
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Abstract
The invention provides solid porous compositions, substantially insoluble in water, comprising at least 25% by weight of an oxidised cellulose and having a significant capacity to bind dissolved iron. The invention also provides a method of sequestering dissolved iron from aqueous environments by bringing said compositions into contact with said environments. The iron-binding property of oxidised cellulose may be used for the prevention or treatment of infections by iron-requiring micro-organisms such as bacteria and yeasts. It may also be used to treat chronic inflammatory lesions or processes where inappropriately available iron is acting as a catalyst for the generation of damaging reactive oxygen species.
112 Citations
19 Claims
- 1. A solid porous composition, substantially insoluble in water, comprising at least 25% by weight of an oxidised cellulose and exhibiting a significant capacity to remove iron from an aqueous environment.
- 5. A method of sequestering dissolved iron from an aqueous solution by bringing the solution into contact with a solid porous composition that is substantially insoluble in water, and which contains at least 25% by weight of an oxidised cellulose.
- 10. Use of a solid porous composition, substantially insoluble in water, comprising at least 25% by weight of an oxidised cellulose for the preparation of a device for the medical or clinical prevention or treatment of a condition caused in whole or in part by inappropriately available iron.
- 16. A method for prevention micro-organism in a mammal comprising administering or applying a therapeutically effective amount of a porous solid that is substantially insoluble in water and contains at least 25% by weight of an oxidised cellulose.
Specification