Perfusion catheter and membrane

• US 20030078539A1
• Filed: 12/27/2000
• Published: 04/24/2003
• Est. Priority Date: 12/27/2000
• Status: Abandoned Application

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Chiu, Jessica, Peterson, Eric D.
• Application Number:
  US09/749,708
• Publication Number:
  US 20030078539A1
• Time in Patent Office: Days
• US Class Current: 604/103.01
• CPC Class Codes: A61M 2025/1095 with perfusion means for enabling blood circulation while the balloon is in an inflated state or in a deflated state, e.g. permanent by-pass within catheter shaft
• CPC Class Codes: A61M 25/104 used for angioplasty
• CPC Class Codes: A61N 2005/1003 having means for centering a radioactive source within the lumen, e.g. balloons
• CPC Class Codes: A61N 5/1002 Intraluminal radiation therapy

Abstract

A catheter having a perfusion section encapsulated by a porous membrane. The catheter can include a shaft to accommodate a radiation source. A spiraled balloon can be positioned about the shaft for centering within a body lumen. Additionally, a longitudinal balloon or mechanical expansion can be provided about the shaft for positioning within a body lumen. A radiotherapy system can be included with a radiation source and a catheter having a perfusion section encapsulated by a porous membrane. A method is provided where a catheter with a perfusion section encapsulated by a porous membrane is advanced through a body lumen. The body lumen is treated by the catheter while a body fluid is perfused past the perfusion section.

Claims

1. A catheter comprising:

a perfusion section; and

a membrane encapsulating a portion of said perfusion section, said membrane having pores.

2. The catheter of claim 1 wherein said membrane is comprised of a polysiloxane related substance.

3. The catheter of claim 1 wherein said perfusion section includes at least one perfusion channel, a portion of said perfusion channel open to a body lumen when said catheter is inserted therein.

4. The catheter of claim 1 wherein said pores include perfusion pores of between about. 0.01 and about 0.05 inches in diameter when said membrane is in an expanded state.

5. The catheter of claim 1 wherein said pores have a concentration of between about 10% and about 50% of a surface area of said membrane when said membrane is in an expanded state.

6. The catheter of claim 1 wherein said membrane further comprises:

a body; and

an end portion adjacent said body, said end portion coupled to a shaft, said shaft extending through said perfusion section.

7. The catheter of claim 6 wherein said pores include access pores throughout said end portion.

8. The catheter of claim 7 wherein said access pores are between about 0.01 and about 0.05 inches in diameter when said membrane is in an expanded state.

9. The catheter of claim 1 further comprising:

a shaft through said perfusion section; and

a perfusion balloon about said shaft.

10. The catheter of claim 9 wherein said shaft includes a shaft lumen to accommodate a radiation source, said perfusion balloon to center said shaft within a body lumen when said catheter is inserted therein.

11. The catheter of claim 9 wherein said perfusion balloon further comprises at least one lobe and said perfusion section includes at least one perfusion channel adjacent said at least one lobe.

12. The catheter of claim 11 wherein said at least one lobe includes a spiraled lobe about said shaft.

13. The catheter of claim 11 wherein said at least one lobe includes a longitudinal lobe parallel said shaft.

14. The catheter of claim 1 further comprising:

a shaft through said perfusion section; and

at least one mechanical expansion coupled to said shaft.

15. The catheter of claim 14 wherein said shaft includes a shaft lumen to accommodate a radiation source, said at least one mechanical expansion to center said shaft within a body lumen when said catheter is inserted therein.

16. A catheter comprising:

a shaft with a lumen there through to accommodate a radiation source;

a spiraled perfusion balloon about said shaft to center said shaft within a body lumen; and

a membrane encapsulating a portion of said perfusion balloon, said membrane having pores.

17. A catheter comprising:

a shaft with a lumen there through to accommodate a radiation source;

at least one longitudinal perfusion balloon about said shaft to position said shaft within a body lumen; and

a membrane encapsulating a portion of said perfusion balloon, said membrane having pores.

18. A catheter comprising:

a shaft with a lumen there through to accommodate a radiation source;

at least one mechanical expansion coupled to said shaft to position said shaft within a body lumen; and

a membrane encapsulating a portion of said perfusion balloon, said membrane having pores.

19. A radiotherapy system comprising:

a radiation source; and

a catheter having a perfusion section with a membrane at least partially thereabout, said membrane having pores.

20. The radiotherapy system of claim 19 wherein said catheter includes a shaft through said perfusion section to accommodate said radiation source, said radiation source comprising a radioactive distal tip of a radiation source wire.

21. A method comprising:

advancing a catheter through a first body lumen, said catheter having a perfusion section with a membrane at least partially thereabout, said membrane having pores;

treating a portion of said first body lumen with a therapy provided by said catheter; and

perfusing a body fluid through said perfusion section during said treating

22. The method of claim 21 further comprising allowing said body fluid access to a second body lumen during said perfusing, said second body lumen intersecting said first body lumen at an opening, said membrane covering said opening.

23. The method of claim 21 wherein said therapy is radiotherapy provided through a shaft of said catheter, said shaft running through said perfusion section.