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High density arrays

  • US 20030082604A1
  • Filed: 08/30/2002
  • Published: 05/01/2003
  • Est. Priority Date: 09/27/2000
  • Status: Abandoned Application
First Claim
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1. A method for generating a microarray, comprising:

  • (a) applying at least one reagent solution containing receptor molecules to a solid support to form a first applied spot pattern, wherein spots in the first applied spot pattern have an area and wherein the reagent solution, the receptor molecules, the solid support, or any combination thereof includes at least one photoreactive group;

    (b) illuminating the first applied spot pattern to immobilize the receptor molecules to the solid support in a first immobilized spot pattern, wherein spots in the first immobilized spot pattern have an area and wherein the area of the spots in the first immobilized spot pattern is less than the area of the spots in the first applied spot pattern.

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