Multichannel electrode and methods of using same
First Claim
1. A multichannel electrode comprising:
- a non-planar backbone comprising a plurality of electrode channels disposed thereon, wherein at least one of said channels has an impedance suitable for recording an electrical signal from a cell and wherein at least one other channel has an impedance suitable for electrical stimulation of a cell.
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Abstract
The invention provides a multichannel electrode (“MC electrode”) which can perform multiple functions such as recording, stimulating and lesioning simultaneously or sequentially upon a single insertion into a target site. In one aspect, the MC electrode further provides imaging and drug delivery capabilities. The invention also provides interface connectors for connecting the MC electrode to external units such as data acquisition and/or stimulation systems. Although the MC electrode and associated connectors and system(s) provide an optimal way to perform deep brain surgical procedures, the MC electrode and associated connectors and system(s) are useful generally in any technique which relies on recording, activating, and/or inhibiting electrical signals produced by cells.
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Citations
67 Claims
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1. A multichannel electrode comprising:
a non-planar backbone comprising a plurality of electrode channels disposed thereon, wherein at least one of said channels has an impedance suitable for recording an electrical signal from a cell and wherein at least one other channel has an impedance suitable for electrical stimulation of a cell. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 64, 65, 66, 67)
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24. A system comprising an interfacing connector for connecting to a multichannel electrode comprising a plurality of channels, at least one channel comprising an impedance suitable for recording and at least one channel suitable for stimulating, said connector comprising:
a housing comprising, a first end and a second end, said first end for connecting to a device for communicating with said multichannel electrode, said second end for receiving said multichannel electrode;
a wall defining a lumen for receiving said multichannel electrode and comprising a plurality of contact points, wherein there is at least one contact point for each channel of said multichannel electrode, and wherein each contact point can transmit an electrical signal to the channel or receive an electrical signal from the channel. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43)
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58. A method of fabricating a multichannel electrode, said method comprising the steps of:
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a) providing a non-planar backbone;
b) coating said non-planar backbone with an electrically conductive material; and
c) laser micro-machining a plurality of channels into said electrically conductive material;
wherein at least one channel comprises an impedance suitable for recording electrical activity of a cell, and wherein at least one channel comprises an impedance suitable for stimulating the electrical activity of a cell.
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59. A method of fabricating fabricating a multichannel electrode, said method comprising the steps of:
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a) providing a first non-planar backbone comprising a lumen;
b) coating said non-planar backbone with an electrically conductive material;
c) laser micro-machining a plurality of channels into said electrically conductive material;
d) providing a second non-planar backbone within said lumen of said first non-planar backbone, said second non-planar backbone coated with an electrically conductive material and comprising a plurality of electrode channels machined thereon;
wherein at least one channel of said multichannel electrode comprises an impedance suitable for recording electrical activity of a cell, and wherein at least one channel comprises an impedance suitable for stimulating the electrical activity of a cell; and
(e) placing said second backbone within said lumen of said first backbone.
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60. A multichannel electrode comprising:
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a first non-planar backbone comprising a lumen; and
a second non-planar backbone disposed within the lumen of the first non-planar backbone;
said first and second backbone each comprising at least one electrode channel, wherein at least one of said channels has an impedance suitable for recording an electrical signal from a cell and wherein at least one other of said channels has an impedance suitable for electrical stimulation of a cell. - View Dependent Claims (61, 62, 63)
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Specification