Blind source separation of pulse oximetry signals
First Claim
1. A method for measuring a physiological parameter, comprising:
- measuring a plurality of signals, wherein each of said signals comprises a source component corresponding to said physiological parameter and an interference component;
processing said plurality of signals to obtain a plurality of principal components;
processing said plurality of principal components to obtain a plurality of independent components, wherein a matrix of said plurality of signals corresponds to a matrix product of a matrix of said plurality of independent components and a matrix of mixing coefficients; and
extracting a first measure of said physiological parameter corresponding to said source component from one of said plurality of independent components.
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Abstract
A method and apparatus for the application of Blind Source Separation (BSS), specifically independent Component Analysis (ICA) to mixture signals obtained by a pulse oximeter sensor. In pulse oximetry, the signals measured at different wavelengths represent the mixture signals, while the plethysmographic signal, motion artifact, respiratory artifact and instrumental noise represent the source components. The BSS is carried out by a two-step method including an ICA. In the first step, the method uses Principal Component Analysis (PCA) as a preprocessing step, and the Principal Components are then used to derive sat and the Independent Components, where the Independent Components are determined in a second step. In one embodiment, the independent components are obtained by high-order decorrelation of the principal components, achieved by maximizing the sum of the squares of the higher-order cumulants of the plurality of mixture signals.
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Citations
40 Claims
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1. A method for measuring a physiological parameter, comprising:
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measuring a plurality of signals, wherein each of said signals comprises a source component corresponding to said physiological parameter and an interference component;
processing said plurality of signals to obtain a plurality of principal components;
processing said plurality of principal components to obtain a plurality of independent components, wherein a matrix of said plurality of signals corresponds to a matrix product of a matrix of said plurality of independent components and a matrix of mixing coefficients; and
extracting a first measure of said physiological parameter corresponding to said source component from one of said plurality of independent components. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A pulse oximeter, comprising:
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a sensor configured for measuring a plurality of signals, wherein each of said signals comprises a source component corresponding to said physiological parameter and an interference component;
a computer useable medium having computer readable code embodied therein for measuring a physiological parameter, said computer readable code configured to execute functions comprising;
processing said plurality of signals to obtain a plurality of principal components;
processing said plurality of principle components to obtain a plurality of independent components, wherein a matrix of said plurality of signals corresponds to a matrix product of a matrix of said plurality of independent components and a matrix of mixing coefficients; and
extracting a first measure of said physiological parameter corresponding to said source component from one of said plurality of independent components. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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Specification