Methods and apparatus for electrosurgical ventriculostomy

• US 20030088245A1
• Filed: 11/04/2002
• Published: 05/08/2003
• Est. Priority Date: 11/02/2001
• Status: Abandoned Application

• Current Assignee: ArthroCare Corporation (Smith & Nephew PLC)
• Original Assignee: ArthroCare Corporation (Smith & Nephew PLC)
• Inventors: Woloszko, Jean, Hovda, David C.
• Application Number:
  US10/288,227
• Publication Number:
  US 20030088245A1
• Time in Patent Office: Days
• US Class Current: 606/41
• CPC Class Codes: A61B 18/148 having a short, rigid shaft for accessing the inner body transcutaneously, e.g. for neurosurgery or arthroscopy
• CPC Class Codes: A61B 2018/00446 Brain

Abstract

Methods and apparatus for electrosurgical treatment of hydrocephalus. A method of the invention comprises electrosurgical fenestration of the floor of the third ventricle using an electrosurgical probe or catheter. The probe or catheter may be introduced via an access hole in the patient'"'"'s cranium. The access hole can be formed mechanically or electrosurgically. A stoma or window in the third ventricle can be enlarged electrosurgically and/or tissue surrounding the stoma can be coagulated, in order to maintain patency of the stoma. According to another aspect of the invention, a method of establishing patency in an occluded cerebral aqueduct comprises guiding an electrosurgical catheter into the cerebral aqueduct, positioning an active electrode in at least close proximity to the occlusion, and applying an ablative voltage to the active electrode to form a channel within the cerebral aqueduct.

Claims

1. A method of fenestrating a third ventricle of a patient, comprising:

a) positioning a distal end of an electrosurgical instrument in at least close proximity to a boundary of a third ventricle of the patient, the instrument having an active electrode and a return electrode, the return electrode spaced from the active electrode; and

b) applying a first high frequency voltage between the active electrode and the return electrode, wherein the first high frequency voltage is sufficient to form a stoma in the boundary of the third ventricle.

2. The method of claim 1, wherein said step a) comprises positioning the active electrode in at least close proximity to an inner boundary of the third ventricle.

3. The method of claim 1, wherein the first high frequency voltage is sufficient to ablate the boundary of the third ventricle in the vicinity of the active electrode.

4. The method of claim 1, wherein the first high frequency voltage simultaneously effects both ablation of a target tissue and hemostasis adjacent to the target tissue.

5. The method of claim 4, wherein the target tissue comprises the floor of the third ventricle.

6. The method of claim 1, wherein said step b) comprises applying the first high frequency voltage in the range of from about 100 volts RMS to 500 volts RMS.

7. The method of claim 1, wherein the stoma is formed by localized volumetric removal of the floor of the third ventricle.

8. The method of claim 1, wherein the stoma allows cerebrospinal fluid to flow from the third ventricle to the interpeduncular cistern.

9. The method of claim 1, further comprising enlarging the stoma.

10. The method of claim 9, wherein the stoma is enlarged electrosurgically by the localized volumetric removal of the boundary of the third ventricle.

11. The method of claim 9, wherein said step c) comprises:

while applying the first high frequency voltage of said step b), manipulating the instrument such that the active electrode is translated laterally with respect to the stoma.

12. The method of claim 9, wherein the stoma is enlarged by placement of a balloon catheter in the stoma.

13. The method of claim 1, wherein the active electrode and the return electrode are independently coupled to a high frequency power supply.

14. The method of claim 13, wherein said step b) comprises applying the first high frequency voltage in an ablation mode, and the method further comprises:

d) after said step b), switching the high frequency power supply to a sub-ablation mode; and

e) thereafter, applying a second high frequency voltage between the active electrode and the return electrode, wherein the second high frequency voltage is sufficient to coagulate tissue adjacent to the stoma.

15. The method of claim 14, wherein said step e) effects hemostasis in the vicinity of the active electrode.

16. The method of claim 14, wherein the second high frequency voltage is in the range of from about 20 volts RMS to 200 volts RMS.

17. The method of claim 1, wherein said step a) comprises introducing a distal end of an endoscope into the third ventricle of the patient.

18. The method of claim 17, wherein the endoscope is introduced into the third ventricle via a foramen of Monro.

19. The method of claim 17, wherein the electrosurgical instrument comprises a catheter, the active electrode disposed at a distal end of the catheter, and the method further comprises:

f) advancing the catheter through the endoscope such that the distal end of the catheter is located within the third ventricle.

20. The method of claim 17, wherein the endoscope is flexible.

21. The method of claim 1, wherein the electrosurgical instrument comprises an electrosurgical probe including a shaft having a shaft distal end, the active electrode disposed at the shaft distal end, and the method further comprises:

g) advancing the shaft distal end through a lumen of a rigid introducer device such that the shaft distal end is located within the third ventricle.

22. A method of performing a third ventriculostomy on a patient, comprising:

a) forming an access hole at a target location in the cranium of the patient;

b) via the access hole, advancing an electrosurgical instrument towards the third ventricle of the patient;

c) positioning an active electrode of the instrument in at least close proximity to a boundary of the third ventricle, the instrument having a return electrode spaced from the active electrode; and

d) applying a first high frequency voltage between the active electrode and the return electrode, wherein the first high frequency voltage is sufficient to form a stoma in the boundary of the third ventricle.

23. The method of claim 22, wherein the target location of said step a) is located up to about 5 cm anterior to the coronal suture and in the range of from about 1 cm to 5 cm from the midline.

24. The method of claim 22, wherein said step a) comprises forming the access hole electrosurgically via plasma-induced volumetric removal of cranium tissue at the target location.

25. The method of claim 22, wherein the access hole comprises a burr hole formed mechanically by a burr.

26. The method of claim 22, wherein the instrument comprises an electrosurgical catheter, and the method further comprises:

e) prior to said step b), introducing an endoscope into the third ventricle.

27. The method of claim 26, wherein said step b) comprises advancing the catheter within the endoscope such that a distal end of the catheter is located within the third ventricle, and wherein the active electrode is disposed on the distal end of the catheter.

28. The method of claim 26, wherein the endoscope is flexible or rigid.

29. The method of claim 22, wherein the instrument comprises an electrosurgical probe, and the method further comprises:

f) prior to said step b), introducing an introducer device into the patient via the access hole.

30. The method of claim 29, wherein the introducer device comprises a rigid tube having a lumen therethrough.

31. The method of claim 30, wherein said step b) comprises passing a distal end of the probe through the lumen of the introducer device.

32. The method of claim 22, wherein the first high frequency voltage is sufficient to effect localized ablation of the boundary of the third ventricle in the vicinity of the active electrode.

33. The method of claim 22, further comprising:

g) enlarging the stoma to form a channel through the boundary of the third ventricle.

34. The method of claim 33, wherein said step g) comprises enlarging the stoma by translating the active electrode laterally with respect to the stoma.

35. The method of claim 22, wherein the active electrode and the return electrode are independently coupled to a high frequency power supply, the high frequency power supply adapted for operating in an ablation mode or a sub-ablation mode.

36. The method of claim 22, further comprising:

h) applying a second high frequency voltage between the active electrode and the return electrode, wherein the second high frequency voltage is sufficient to effect hemostasis in the vicinity of the active electrode.

37. The method of claim 36, wherein the first high frequency voltage is in the range of from about 100 volts RMS to 500 volts RMS, and the second high frequency voltage is in the range of from about 20 volts RMS to 200 volts RMS.

38. The method of claim 36, wherein the second high frequency voltage serves to stiffen tissue adjacent to the stoma.

39. The method of claim 22, wherein said step c) comprises positioning the active electrode in at least close proximity to a floor of the third ventricle.

40. The method of claim 22, wherein the stoma in the boundary of the third ventricle allows excess cerebrospinal fluid to drain from the third ventricle, and symptoms of obstructive hydrocephalus are alleviated.

41. The method of claim 22, wherein the instrument includes at least one depth marking, and said step b) comprises monitoring a location of the at least one depth marking with respect to the cranium at the target location.

42. The method of claim 22, wherein at least one of said step b) or said step c) is performed under fluoroscopy.

43. The method of claim 22, wherein the instrument includes a tracking unit, the tracking unit disposed at a shaft distal end of the instrument, and the method further comprises:

after said step a), monitoring a location of the shaft distal end of the instrument within the patient.

44. The method of claim 22, wherein the instrument further includes a coagulation electrode adapted for coagulating tissue and for effecting hemostasis.

45. A method of forming an access hole in the cranium of a patient using an electrosurgical probe, comprising:

a) positioning an active electrode of the probe in at least close proximity to a target location of the cranium;

b) delivering an electrically conductive fluid to the active electrode or to the target location; and

c) applying a high frequency voltage between the active electrode and a return electrode, wherein the high frequency voltage is sufficient to locally ablate tissue at the target location, whereby the access hole is formed in the cranium at the target location.

46. The method of claim 45, wherein the electrically conductive fluid provides a current flow path between the active electrode and the return electrode.

47. The method of claim 45, wherein the high frequency voltage is sufficient to effect the controlled removal of cranium tissue at the target location.

48. The method of claim 45, wherein the access hole has a diameter in the range of from about 2 mm to 8 mm.

49. The method of claim 45, wherein the high frequency voltage applied in said step c) is in the range of from about 100 volts RMS to 1800 volts RMS.

50. The method of claim 45, wherein the probe includes a fluid delivery element for delivering the electrically conductive fluid to the distal end of the probe or to the target location.

51. The method of claim 45, wherein said step b) comprises placing an electrically conductive gel on the scalp of the patient at the target location.

52. The method of claim 45, wherein the probe includes an aspiration unit, and the method further comprises:

d) aspirating tissue fragments and excess electrically conductive fluid from the target location.

53. A method of establishing patency in a cerebral aqueduct of a hydrocephalus patient, comprising:

a) introducing a distal end of an electrosurgical catheter into the cerebral aqueduct of the patient, wherein the catheter includes an electrode assembly disposed on the distal end, the electrode assembly including an active electrode and a return electrode; and

b) applying a first high frequency voltage between the active electrode and the return electrode, the first high frequency voltage sufficient to ablate tissue, wherein tissue adjacent to the active electrode is volumetrically removed and patency of the cerebral aqueduct is established.

54. The method of claim 53, wherein the first high frequency voltage is in the range of from about 100 volts RMS to 500 volts RMS.

55. The method of claim 53, wherein said step a) comprises positioning the active electrode in at least close proximity to a target tissue.

56. The method of claim 55, wherein the target tissue comprises an occlusion of the cerebral aqueduct.

57. The method of claim 53, further comprising:

c) during said step b), axially translating the active electrode.

58. The method of claim 55, wherein the target tissue occludes the cerebral aqueduct, and wherein volumetric removal of the target tissue forms a channel between a third ventricle and a fourth ventricle of the patient.

59. The method of claim 58, further comprising:

d) while the electrode assembly is positioned within the channel, applying a second high frequency voltage between the active electrode and the return electrode, the second high frequency voltage selected to coagulate tissue adjacent to the channel.

60. The method of claim 59, wherein the second high frequency voltage is in the range of from about 20 volts RMS to 200 volts RMS.

61. The method of claim 59, wherein hemostasis within the cerebral aqueduct is effected by said step b) or by said step d).

62. The method of claim 59, wherein symptoms associated with aqueductal stenosis are alleviated or eliminated.

63. An apparatus for performing electrosurgical third ventriculostomy on a hydrocephalus patient, the apparatus comprising:

a shaft having a shaft distal end and a shaft proximal end, the shaft having at least one depth marking thereon, the shaft distal end adapted for passage into a third ventricle of the patient via a foramen of Monro, and the shaft having a diameter in the range of from about 1 mm to 5 mm;

an electrode assembly disposed at the shaft distal end, the electrode assembly including a distal active electrode and a proximal return electrode, the return electrode spaced from the active electrode by an electrically insulating spacer; and

a tracking unit disposed at the shaft distal end, the tracking unit adapted for monitoring a location of the shaft distal end with respect to the third ventricle of the patient.

64. The apparatus of claim 63, further comprising an introducer device adapted for insertion in an access hole in the cranium of the patient, the introducer device having an introducer lumen therethrough, the introducer lumen adapted for passage of the shaft distal end therethrough.

65. The apparatus of claim 63, wherein the electrode assembly further includes a coagulation electrode.

66. The apparatus of claim 63, further comprising a high frequency power supply, the active electrode and the return electrode independently coupled to the high frequency power supply via a connection block.

67. The apparatus of claim 66, further comprising a voltage reduction element coupled between the power supply and the active electrode.

68. The apparatus of claim 63, wherein at least the shaft distal end is steerable to a specific target site within the patient.

69. The apparatus of claim 63, wherein the shaft consists essentially of a nonmetallic material.

70. The apparatus of claim 63, wherein the shaft has a bend at an angle in the range of from about 15°

to 45°

.

71. The apparatus of claim 63, wherein the tracking unit comprises a radiopaque material.