Treatment and composition for achieving skin anti-aging benefits by corneum protease activation
First Claim
1. A method of treating skin comprising topical application to aged or damaged skin of a cosmetic composition comprising a chemically compatible combination of one or more surfactants and at least one chelating agent, in an amount effective to provide chronic stimulation of said skin'"'"'s stratum corneum turnover rate, and a reduction in said stratum corneum turnover time, by activating one or more of said skin'"'"'s endogenous corneum protease enzymes.
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Accused Products
Abstract
Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin'"'"'s visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin'"'"'s stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin'"'"'s stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.
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Citations
41 Claims
- 1. A method of treating skin comprising topical application to aged or damaged skin of a cosmetic composition comprising a chemically compatible combination of one or more surfactants and at least one chelating agent, in an amount effective to provide chronic stimulation of said skin'"'"'s stratum corneum turnover rate, and a reduction in said stratum corneum turnover time, by activating one or more of said skin'"'"'s endogenous corneum protease enzymes.
- 13. The method according to claim 13 wherein said treatment is effective to decrease number of wrinkles on the canthus by from about 1% to about 60%.
- 28. A cosmetic treatment composition for aged or damaged skin comprising a chemically compatible combination of one or more surfactants and at least one chelating agent, in an amount effective to provide chronic stimulation of said skin'"'"'s stratum corneum turnover rate, and a reduction in said stratum corneum turnover time, by activating one or more of said skin'"'"'s endogenous corneum protease enzymes.
Specification