Gel-infused sponges for tissue repair and augmentation
First Claim
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1. A gel-infused sponge matrix comprising a porous biodegradable sponge material infused with a gel precursor.
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Abstract
Gel-infused sponge matrix comprising an absorbable sponge material, a gel and an active ingredient are disclosed, as are methods of enhancing tissue repair, regeneration or augmentation using the gel-infused sponge.
109 Citations
30 Claims
- 1. A gel-infused sponge matrix comprising a porous biodegradable sponge material infused with a gel precursor.
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22. A process for the preparation of a gel-infused matrix material, wherein said gel-infused matrix material is comprised of a porous biodegradable matrix material infused with a gel precursor, and wherein the process is comprised of the following steps:
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(1) soaking said porous biodegradable matrix material in a gel containing bioactive agents;
(2) compressing said porous biodegradable matrix material to extrude out air; and
(3) slowly releasing the matrix allowing the porous biodegradable matrix material to fully absorb the gel precursor. - View Dependent Claims (23, 24, 25, 26, 27)
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28. A method of implanting a gel-infused matrix material for the promotion of tissue growth, regeneration, repair or augmentation.
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29. A method of implanting a gel-infused matrix material for the promotion of bone, cartilage, meniscus or nerve growth, regeneration, repair or augmentation.
Specification