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Novel long-term three-dimensional tissue culture system

  • US 20030096411A1
  • Filed: 10/28/2002
  • Published: 05/22/2003
  • Est. Priority Date: 12/07/1999
  • Status: Abandoned Application
First Claim
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1. A method for generating a hepatic cell culture comprising co-culturing hepatocytes and nonparenchymal cells, in the presence of growth factors corticosteroid and a matrix coated with at least one biologically active molecule that promotes cell adhesion, proliferation or survival under conditions sufficient to allow for the proliferation of hepatocytes that retain hepatic function.

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