Disinfectant and antiseptic composition

• US 20030099717A1
• Filed: 06/10/2002
• Published: 05/29/2003
• Est. Priority Date: 06/15/2001
• Status: Active Grant

• Current Assignee: Oftrai, S.L.
• Original Assignee: Oftrai, S.L.
• Inventors: Cabrera, Rafael Herruzo
• Granted Patent: US 6,908,628 B2
• Time in Patent Office: Days
• US Class Current: 424/616
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/30 characterised by the surfactants
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 37/02 Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
• CPC Class Codes: A01N 37/36 containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
• CPC Class Codes: A01N 37/46 N-acyl derivatives
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof
• CPC Class Codes: A01N 59/00 Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• CPC Class Codes: A01N 59/12 Iodine, e.g. iodophors; Compounds thereof
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A01N 61/00 Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
• CPC Class Codes: A61L 2/186 Peroxide solutions
• CPC Class Codes: A61L 2202/24 Medical instruments, e.g. endoscopes, catheters, sharps

Abstract

Wide spectrum disinfecting and antiseptic composition for use in the fields of human medicine, veterinary science and industry, characterized because it includes:

Hydrogen peroxide, lactic acid and halogen salts (Br, I) and/or salts of heavy metals (for example, silver halides) with surfactant agents, either cationic, like chlorhexidine and/or quaternary ammonium salts, like didecyl-methyl-polyoxy-ethyl-ammonium propionate, chlorides of ammonium or compounds of ammonium propylamide or anionic, like lauryl sulphate, dodecyl sulphate or alkyl succinic salts, with suitable excipients, some of which may be ethyl or isopropyl alcohol, chlorhexidine, non-chlorinated quaternary ammonium salts, like didecyl-methyl-polyoxy-ethyl-ammonium propionate, combined or not with iodine, and/or its salts, together with excipients, some of which may be ethyl or isopropyl alcohol.

Claims

1. A disinfecting and antiseptic composition, characterised in that it comprises a mixture of oxidising substances, like hydrogen peroxide, lactic acid plus halogen salts (Br, I) and or heavy metal salts (for example, silver halides), surfactants, whether cationic of the biguanidine type, like chlorhexidine and/or chlorinated or non-chlorinated quaternary ammonium salts or, in some cases, anionic ones (like lauryl sulphate, alkyl succinic or dodecyl sulphate), eventually plus metallic iodine or its salts, together with suitable excipients, some of which may be alcohol.

2. A composition according to claim 1, comprising from 0.2-2.9% or from 6.1-22.5% hydrogen peroxide with respect to the total in its undiluted formulations.

3. A composition according to claim 1, comprising 0.1-24% lactic acid with respect to the total in its undiluted formulations.

4. A composition according to claim 1, comprising 3.1-20% lauryl sulphate salts, with respect to the total in its undiluted formulations.

5. A composition according to claim 1, comprising 0.2-12% dodecyl sulphate salts, with respect to the total in its undiluted formulations.

6. A composition according to claim 1, comprising 0.2-12% alkyl succinic salts, with respect to the total in its undiluted formulations.

7. A composition according to claim 1, comprising 5.1-18% biguanidines like chlorhexidine, with respect to the total in its undiluted formulations.

8. A composition according to claim 1, comprising 0.01-18% biguanidines, like chlorhexidine, with respect to the total in its undiluted formulations.

9. A composition according to claim 1, comprising 0.2-50% quaternary ammonium salts like didecyl-methyl-polyoxy-ethyl-ammonium propionate, ammonium chlorides or compounds of ammonium propylamide, with respect to the total in its undiluted solutions.

10. A composition according to claim 1, comprising 0.2-50% non-chlorinated quaternary ammonium salts like didecyl-methyl-polyoxy-ethyl-ammonium propionate, with respect to the total in its undiluted formulations.

11. A composition according to claim 1, comprising 0.0002-0.1% heavy metal salts, like silver halides, with respect to the total in its undiluted formulations.

12. A composition according to claim 1, comprising 0.1-5% iodine or its salts with respect to the total in its undiluted formulations.

13. A composition according to claim 1, comprising 1-10 units/ml final mixtures of enzymes, like trypsin and/or amylase and/or lipase in its undiluted formulations.

14. A composition according to claim 1, comprising:

15. A composition according to claim 1, comprising:

16. A composition according to claim 1, comprising:

17. A composition according to claim 1, comprising:

18. A composition according to claim 1, comprising:

19. A composition according to claim 1, comprising the formulations of claims 15-19 to which enzymes are incorporated, selected from trypsin and/or amylase and/or lipase, to give an enzymatic detergent.

20. A composition according to claim 1, comprising:

didecyl-methyl-polyoxy-ethyl-ammonium propionate or other non-chlorinated quaternary ammonium salts;

0.2-50%

chlorhexidine;

0.1-18%

iodine or its salts;

0.1-5%

water and excipients (balance until 100%)

where all the percentages are by weight with respect to the total composition in the undiluted formulations.

21. A composition according to claim 1, comprising:

didecyl-methyl-polyoxy-ethyl-ammonium propionate or other non-chlorinated quaternary ammonium salts;

0.2-50%

chlorhexidine;

0.1-18%

iodine or its salts;

0.1-5%

ethyl or isopropyl alcohol (60°

) (balance until 100%)

where all the percentages are by weight with respect to the total composition in the undiluted formulations.

22. A method to disinfect instruments for hospital use, comprising the application of a suitable amount of a disinfecting and antiseptic composition according to any of the claims 1 to 20, on the instruments to be disinfected.

23. A method to disinfect conduits and surfaces of hospital environment, comprising the application of a suitable amount of a disinfecting and antiseptic composition according to any of the claims 1 to 20, on the conduits and surfaces to be disinfected.

24. A method to disinfect equipment, instruments, conduits and surfaces of industrial facilities, comprising the application of a suitable amount of a disinfecting and antiseptic composition according to any of the claims 1 to 20, on the equipment, instruments, conduits and surfaces of the industrial facility to be disinfected.

25. A method and products with or without alcohol, with or without iodine, for skin antisepsis in the human or veterinary field, according to claims 1, 21 and 22.