Simultaneous cleaning and decontaminating compositions and methods
First Claim
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1. A composition for simultaneous cleaning and decontaminating a device comprising:
- a) a per-compound oxidant in an amount effective for decontaminating, and b) an enzyme in an amount effective for cleaning said device.
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Abstract
A composition for simultaneous cleaning and decontaminating a device. The composition is a per-compound oxidant in an amount effective for decontaminating the device and an enzyme in an amount effective for cleaning the device. The device may be a medical device such as an endoscope or kidney dialyzer and a plurality of devices can be cleaned using the same composition. The composition may additionally contain a corrosion inhibitor in an amount effective to prevent corrosion of a metal, a chelator, a buffer, a dye and combinations thereof.
54 Citations
77 Claims
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1. A composition for simultaneous cleaning and decontaminating a device comprising:
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a) a per-compound oxidant in an amount effective for decontaminating, and b) an enzyme in an amount effective for cleaning said device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 69, 71, 73)
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29. A method for simultaneously cleaning and decontaminating a device comprising the steps of:
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a) first, removing loosely adhering soil from said device, b) second, contacting said device with a solution that simultaneously cleans and decontaminates said device, said solution comprising a per-compound oxidant in an amount effective for decontaminating and an enzyme in an amount effective for cleaning, and c) third, removing said solution from said device. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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- 51. A method for simultaneously cleaning and decontaminating a device comprising contacting said device with a solution that simultaneously cleans and decontaminates said device, said solution comprising a per-compound oxidant in an amount effective for decontaminating and an enzyme in an amount effective for cleaning.
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74. A method for simultaneously cleaning and decontaminating a kidney dialyzer comprising contacting said dialyzer with a solution that simultaneously cleans and decontaminates said dialyzer, said solution comprising a mixture of H2O2 at about 0.5-1.5%w/w and PAA at about 0.05-3.0%w/w and human pepsin at about 0.00001-0.10 A.U./ml and having a pH between 1-6.
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75. A composition for simultaneously cleaning and decontaminating a kidney dialyzer comprising a mixture of H2O2 at about 0.5-1.5%w/w and PAA at about 0.05-3.0%w/w and human pepsin at about 0.00001-0.10 A.U./ml and having a pH between 1-6.
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76. A method for simultaneously cleaning and decontaminating a kidney dialyzer comprising contacting said dialyzer with a solution that simultaneously cleans and decontaminates said dialyzer, said solution comprising a mixture of H2O2 at about 0.5-1.5%w/w and PAA at about 0.05-3.0%w/w and human trypsin at about 0.00001-0.10 A.U./ml and having a pH between 6-9.
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77. A composition for simultaneously cleaning and decontaminating a kidney dialyzer comprising a mixture of H2O2 at about 0.5-1.5%w/w and PAA at about 0.05-3.0%w/w and human trypsin at about 0.00001-0.10 A.U./ml and having a pH between 6-9.
Specification