Hydrogel for the therapeutic treatment of aneurysms
First Claim
1. A method for treating an aneurysm, the aneurysm having a dome portion and a neck opening into a parent vessel, the method comprising the steps of:
- introducing an occlusive, embolus generating device into the aneurysm; and
delivering a hydrogel into the dome portion of the aneurysm and adjacent to the neck of the aneurysm, the hydrogel containing a radiopaque material and a growth factor that is released from the hydrogel in the aneurysm to promote cellular growth across the neck of the aneurysm.
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Accused Products
Abstract
The hydrogel for the treatment of aneurysms acts as a carrier for both a radiopaque agent allowing the hydrogel to be visualized under fluoroscopy and a therapeutic agent such as one or more human growth factors. The hydrogel is delivered through a catheter into the aneurysm, where the hydrogel becomes more viscous upon reaching body temperature, or upon exposure to bodily fluids, to block blood flow into the aneurysm. In addition to stopping blood flow into the aneurysm, the delivery of human growth factors to the aneurysm site promotes the growth of a cellular layer across the neck of the aneurysm. The hydrogel may be of a type that dissolves over time or one which remains as a permanent occlusive agent within the aneurysm.
64 Citations
9 Claims
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1. A method for treating an aneurysm, the aneurysm having a dome portion and a neck opening into a parent vessel, the method comprising the steps of:
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introducing an occlusive, embolus generating device into the aneurysm; and
delivering a hydrogel into the dome portion of the aneurysm and adjacent to the neck of the aneurysm, the hydrogel containing a radiopaque material and a growth factor that is released from the hydrogel in the aneurysm to promote cellular growth across the neck of the aneurysm. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification