Treatment of skin wounds using polyenylphosphatidylcholine and alkanolamines
First Claim
1. A method for the treatment of skin wounds comprising topically applying to the skin a composition containing an effective amount of polyenylphosphatidylcholine and an effective amount of an alkanolamine of the formula
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Abstract
Polyenylphosphatidylcholine in combination with an alkanolamine are topically applied to treat skin wounds, promote healing, and minmize scar formation. Typical compositions contain from about 0.25% to about 12% of a polyenylphosphatidylcholine preparation obtained from natural sources such as soybean oil which contains at least about 25% by weight, preferably about 40% or more, dilinoeoylphosphatidylcholine, and from about 0.1% to about 10% by weight of an alkanolamine such as ethylaminoethanol, methylaminoethanol, dimethylaminoethanol, isopropanolamine, triethanolamine, isopropanoldimethylamine, ethylethanolamine, 2-butanolamine, choline, serine, or mixtures thereof. Dimethylaminoethanol is a particularly preferred alkanolamine. Tyrosine is an adjunct ingredient in many embodiments.
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Citations
30 Claims
- 1. A method for the treatment of skin wounds comprising topically applying to the skin a composition containing an effective amount of polyenylphosphatidylcholine and an effective amount of an alkanolamine of the formula
- 14. A bandage impregnated with a composition containing an effective wound-healing amount of polyenylphosphatidylcholine and an alkanolamine selected from the group consisting of ethylaminoethanol, methylaminoethanol, dimethylaminoethanol, isopropanolamine, triethanolamine, isopropanoldimethylamine, ethylethanolamine, 2-butanolamine, choline, serine, and mixtures thereof.
- 22. A method for the treatment of skin wounds comprising topically applying to the skin a composition containing an effective wound-healing amount of polyenylphosphatidylcholine and another composition containing an alkanolamine selected from the group consisting of ethylaminoethanol, methylaminoethanol, dimethylaminoethanol, isopropanolamine, triethanolamine, isopropanoldimethylamine, ethylethanolamine, 2-butanolamine, choline, serine, and mixtures thereof.
- 25. A composition for treating skin wounds comprising polyenylphosphatidylcholine and an alkanolamine of the formula
Specification