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Methods of blocking tissue destruction by autoreactive T cells

  • US 20030106084A1
  • Filed: 04/10/2002
  • Published: 06/05/2003
  • Est. Priority Date: 03/29/2000
  • Status: Abandoned Application
First Claim
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1. A method for inhibiting autoreactive T cell-initiated destruction of tissues in a mammal comprising:

  • administering a pharmaceutical composition to the mammal, said pharmaceutical composition comprising an agent selected from the group consisting of;

    an isolated HSA/CD24 polypeptide, an isolated biologically active fragment of an HSA/CD24 polypeptide, a fusion protein comprising an HSA/CD24 polypeptide, a fusion protein comprising a biologically active fragment of an HSA/CD24 polypeptide, and an anti-HSA/CD24 antibody;

    wherein said pharmaceutical composition is administered in an amount sufficient to reduce autoreactive T cell-initiated tissue destruction in said mammal.

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