Drug delivery system and method

• US 20030109827A1
• Filed: 12/07/2001
• Published: 06/12/2003
• Est. Priority Date: 12/07/2001
• Status: Abandoned Application

• Current Assignee: Elan Pharma International Limited (Perrigo Company PLC)
• Original Assignee: Elan Pharma International Limited (Perrigo Company PLC)
• Inventors: Lavi, Gilad, Ygal, Gil, Tsals, Israil
• Application Number:
  US10/010,624
• Publication Number:
  US 20030109827A1
• Time in Patent Office: Days
• US Class Current: 604/134
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/14506 mechanically driven, e.g. spring or clockwork
• CPC Class Codes: A61M 5/141 with capillaries for restricting fluid flow
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump

Abstract

A system and method for delivering drug solutions to a user, the system having a housing with a drug reservoir therein. The system also includes an activation assembly having a delivery needle and an activation device for activating delivery. The system further includes a pump, associated with the drug reservoir and a flow restrictor. When activated, the pump moves the drug out of the drug reservoir through the delivery needle and into the skin of the user. The pump may be in the form of a spring.

Claims

1. A drug delivery system comprising:

a housing;

a drug reservoir received into the housing;

an activation assembly comprising a delivery needle for insertion into the skin of a user upon activation, and an activation device for activating delivery of drug into the skin;

a channel to effect liquid communication between the drug reservoir and delivery needle upon receipt of the drug reservoir into the housing;

a flow restrictor in communication with the moveable channel to restrict the flow of drug therethrough; and

a pump for moving drug out of the drug reservoir, through the delivery needle and into the user when activated.

2. The system of claim 1 wherein the drug reservoir comprises a drug cartridge having a stopper at one end.

3. The system of claim 2 wherein the drug cartridge is received into a recess in the housing.

4. The system of claim 2 wherein the channel comprises a needle capable of piercing the stopper of the drug reservoir.

5. The system of claim 1 wherein the activation device activates liquid communication between the drug reservoir and the delivery needle.

6. The system of claim 1 wherein the activation device activates insertion of the delivery needle into the skin of the user.

7. The system of claim 1 wherein the flow restrictor is a length of flexible tubing.

8. The system of claim 7 wherein the tubing diameter is in the range of between 0.2 and 0.05 mm.

9. The system of claim 1 wherein the delivery needle is a 26 gauge needle.

10. The system of claim 1 wherein the drug has a viscousity of up to 150 cp.

11. The system of claim 7 wherein the tubing length is in the range of between 40 and 140 mm.

12. The system of claim 1 wherein the pump comprises a spring that applies pressure to the drug reservoir thereby forcing drug out of the drug reservoir.

13. The system of claim 10 wherein the pressure applied by the spring is in the range of between 400 and 1000 mbar.

14. The system of claim 7 wherein the tubing is made of plastic.

15. The system of claim 1 wherein the delivery needle moves from a first stored position, to a second delivery position when the delivery needle is moved into the skin of a user, to a third locked position within the housing of the system.

22. The device of claim 1 further comprising a layer of adhesive on the bottom of the housing to adhere the housing to the user'"'"'s skin.

16. A method of delivering drug to a user comprising the steps of:

providing a drug delivery system having a housing, a drug reservoir, an activation assembly, the activation assembly having a delivery needle for insertion into the skin of a user, and an activation device for activating the insertion of the delivery needle into the skin, and a channel to effect liquid communication between the drug reservoir and delivery needle upon activation;

activating the system thereby causing liquid communication between the drug reservoir and the delivery needle;

moving drug out of the drug reservoir, through the delivery needle and into the user; and

restricting the flow of drug along the channel between the drug reservoir and the delivery needle.

17. The method of claim 16 wherein the drug reservoir comprises a drug cartridge having a stopper at one end.

18. The method of claim 17 wherein the step of moving drug out of the reservoir is accomplished by applying force to the stopper.

19. The method of claim 18 wherein the step of applying force is accomplished through the use of a spring.

20. The method of claim 16 wherein the step of restricting the flow is accomplished by causing the drug to flow from the drug reservoir into a length of tubing and into the delivery needle.

21. The method of claim 16 further comprising the step of adhering the system to the user'"'"'s skin prior to step of activating the system.