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Method of matching retention times among multiple chromatographic system

  • US 20030110000A1
  • Filed: 11/30/2001
  • Published: 06/12/2003
  • Est. Priority Date: 11/30/2001
  • Status: Active Grant
First Claim
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1. A process for correcting a time axis of local chromatographic data to match reference chromatographic data while maintaining peak areas, comprising:

  • obtaining reference calibration data from a reference chromatographic system;

    obtaining local calibration data from a local chromatographic system;

    generating local system correction functions based on an appropriate mathematical relationship using the reference calibration and the local calibration data; and

    applying the local system correction functions to local chromatographic data to generate corrected local chromatographic data, wherein the corrected local chromatographic data match with the reference calibration data on time axis and wherein peak areas in the local chromatographic data are maintained in the corrected local chromatographic data.

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