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POSITIONAL SEQUENCING BY HYBRIDIZATION

  • US 20030118987A1
  • Filed: 02/24/1998
  • Published: 06/26/2003
  • Est. Priority Date: 11/06/1992
  • Status: Active Grant
First Claim
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1. A method for creating an array of probes comprising the steps of:

  • a) synthesizing a first set of nucleic acids each comprising a constant sequence of length C at 3′

    -terminus and a random sequence of length R at a 5′

    -terminus;

    b) synthesizing a second set of nucleic acids each comprising a sequence complimentary to the constant sequence of each of the first nucleic acid; and

    c) hybridizing the first set with the second set to create the array.

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