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Solid-phase reactions

  • US 20030119020A1
  • Filed: 07/17/2002
  • Published: 06/26/2003
  • Est. Priority Date: 07/17/2001
  • Status: Active Grant
First Claim
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1. A method for detecting polymorphisms in unamplified DNA, comprising:

  • a. providing;

    i. unamplified DNA;

    ii. reagents for conducting an invasive cleavage reaction, wherein at least one of said reagents is attached to a solid surface;

    b. treating said unamplified DNA with said reagents under conditions such that the presence or absence of a polymorphism in said genomic DNA is identified.

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