Ablation therapy

• US 20030120270A1
• Filed: 04/23/2002
• Published: 06/26/2003
• Est. Priority Date: 04/23/2001
• Status: Abandoned Application

• Current Assignee: ProRhythm, Inc.
• Original Assignee: Transurgical, Inc.
• Inventors: Acker, David E.
• Application Number:
  US10/131,755
• Publication Number:
  US 20030120270A1
• Time in Patent Office: Days
• US Class Current: 606/41
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2017/003 Steerable
• CPC Class Codes: A61B 2017/22069 Immobilising; Stabilising
• CPC Class Codes: A61B 2017/2929 with a head rotatable about the longitudinal axis of the shaft
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00285 Balloons
• CPC Class Codes: A61B 2018/00375 Ostium, e.g. ostium of pulmonary vein or artery
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/1475 Electrodes retractable in or deployable from a housing
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

Methods and apparatus for treating cardiac arrhythmias by ablating myocardial fibers within a pulmonary vein through use of a catheter. For example, the ablative element of the catheter is rotated around an axis to ablate a partial or complete loop of tissue within the pulmonary vein so as to block the transmission into the cardiac tissue of electrical signals originating or propagating from myocardial fibers within a pulmonary vein. In other examples, signals from the catheter are monitored to determine whether the ablative element is in contact with the wall of the pulmonary vein. Additional apparatus allow precise angular positioning of the ablative element within the lumen of the pulmonary vein. Apparatus and methods for detecting the properties of the tissue within the pulmonary vein, locating myocardial fibers, selectively ablating such fibers, and determining if such fibers are ablated are also disclosed.

Claims

1. A method of treating cardiac arrhythmias, comprising:

locating mycocardial fibers within a pulmonary vein;

ablating said myocardial fibers within said pulmonary vein;

determining whether electrical signals can be propagated through said myocardial fibers such that arythmogenic signals can be transmitted; and

repeating said ablating step if said electrical signals can be propagated through said myocardial fibers such that said arythmogenic signals can be transmitted.

2. A method as claimed in claim 1, further comprising the steps of:

applying a signal to said myocardial fibers; and

determining the magnitude of such signal transmitted trough said myocardial fibers.

3. A method as claimed in claim 2, further comprising the step of determining the magnitude of such signals around the circumference of said pulmonary vein.

4. A method as claimed in claim 2, further comprising the step of determining whether the ablation device is in contact with the wall of the pulmonary vein.

5. An ablation apparatus, comprising:

(a) a carrier catheter having a proximal and a distal end, a longitudinal bore from said proximal to said distal end, an axis, and an aperture communicating with said longitudinal bore, said aperture being between said proximal and said distal end;

(b) a treatment catheter having a distal portion, said distal portion disposed slidably within said longitudinal bore, wherein said distal portion is positionable such that at least a portion of said distal portion of said treatment catheter can pass through said aperture and project away from said axis; and

(c) an ablation device on said distal portion of said treatment catheter, whereby rotating said carrier catheter about said axis causes said ablation device to traverse a circular path.

6. An ablation apparatus as claimed in claim 5, further comprising a device to determine the angular rotation of said carrier catheter about said axis.

7. An ablation apparatus comprising:

(a) at least one catheter having a proximal end and a distal end, said at least one catheter including a distal portion adjacent said distal end, said distal portion defining an axis and radial directions transverse to said axis;

(b) an ablation device carried on said at least one catheter, said ablation device being movable between an inoperative position and an operative position in which said ablation device is adjacent said distal portion of said catheter and is remote from said axis, said ablation device moving with a component of motion in a radially outward direction in movement from said inoperative position to said operative position; and

(c) a rotation drive mechanism linked to said ablation device and operative to swing said ablation device about said axis while said ablation device is in said operative position.

8. Apparatus as claimed in claim 7 wherein said at least one catheter includes a carrier catheter and a treatment catheter, said ablation device being mounted on said treatment catheter.

9. Apparatus as claimed in claim 8 wherein said rotation drive mechanism is connected between said carrier catheter and said treatment catheter, and wherein said rotation drive mechanism is operative to rotate said treatment catheter relative to said carrier catheter.

10. An apparatus for positioning a catheter, comprising:

a carrier catheter having a proximal end, a distal end, a longitudinal bore from said proximal to said distal end, and an engaging portion between said proximal end and said distal end; and

a treatment catheter having a distal portion and a mating portion, said distal portion disposed slidably within said longitudinal bore, wherein said mating portion engages with said engaging portion of said carrier catheter such that moving said treatment catheter slidably within said carrier catheter rotates said treatment catheter.

11. An apparatus for positioning a catheter, comprising:

a carrier catheter having a proximal end, a distal end, and an engaging portion between said proximal end and said distal end; and

a treatment catheter having a distal portion and a mating portion, said distal portion disposed slidably on said carrier catheter, wherein said mating portion engages with said engaging portion of said carrier catheter such that moving said treatment catheter slidably on said carrier catheter between said proximal end and said distal end rotates said treatment catheter.

12. An apparatus for positioning a catheter, compromising:

a carrier catheter having a proximal portion and a distal portion, said proximal and distal portions defining an axis;

a second catheter having a distal portion, and an distal end, said distal portion of said second catheter disposed slidably relative to said carrier catheter such that sliding said second catheter relative to said carrier catheter results in movement of the distal end of said second catheter transverse to said axis of said carrier catheter.

13. An apparatus as claimed in claim 12, wherein said transverse movement is radial to said axis.