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Methods for predicting transcription levels

  • US 20030120433A1
  • Filed: 10/17/2002
  • Published: 06/26/2003
  • Est. Priority Date: 10/17/2001
  • Status: Abandoned Application
First Claim
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1. A method for predicting an expression level of a target gene or gene family comprising:

  • a) selecting a target gene or gene family;

    b) experimentally determining the number and type of cis-acting elements and mRNA expression levels of other genes within said target gene family to obtain a first data set; and

    c) applying a PROBE algorithm to said data set, thereby generating the estimated expression level of said target gene as a function of the weighed frequencies of said cis-acting elements present in the 5′

    untranslated regulatory region of said target gene.

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