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Imaging microarrays

  • US 20030124589A1
  • Filed: 10/11/2002
  • Published: 07/03/2003
  • Est. Priority Date: 10/12/2001
  • Status: Active Grant
First Claim
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1. A method of obtaining a corrected image of a microarray, the method comprising:

  • acquiring an image of a microarray including a target spot;

    processing the image to correct for background noise and chip misalignment;

    analyzing the image to identify a target patch, edit debris, and correct for ratio bias; and

    , detecting single copy number variation in the target spot using an objective statistical analysis that includes a t-value statistical analysis.

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