Devices and methods for delivery of medically appropriate fluids

• US 20030130645A1
• Filed: 09/19/2002
• Published: 07/10/2003
• Est. Priority Date: 12/03/2001
• Status: Abandoned Application

• Current Assignee: Tandem Medical, Inc.
• Original Assignee: Tandem Medical, Inc.
• Inventors: Lieberman, Marc S., Brengle, David R., Fennelly, Jeremy D., Glazerman, Daniel Z., Doyle, Mark C.
• Application Number:
  US10/251,941
• Publication Number:
  US 20030130645A1
• Time in Patent Office: Days
• US Class Current: 604/500
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407

Abstract

The present invention relates to delivery containers designed to deliver fluids for infusion to patients in a predetermined sequence, and methods for their construction and use. The containers described herein integrally comprise a plurality of non-fluidly connected chambers. The containers may be configured to deliver a volume of each medication of an infusion therapy in a predetermined sequence, duration, and/or interval from these chambers; alternatively, a container may be part of a larger device that provides the necessary hardware to perform such predetermined delivery. The container provides improved infusion therapy administration by reducing opportunities for error, infection, adverse drug interactions, or other complications.

Claims

1. A method of providing a therapy regimen to a patient, said therapy regimen comprising the delivery in a predetermined sequence of a plurality of fluids from an integral container to said patient, said integral container comprising said plurality of fluids contained within separate non-fluidly connected chambers, the method comprising:

delivering said plurality of fluids from said separate non-fluidly connected chambers to said patient in said predetermined sequence.

2. The method of claim 1, wherein said plurality of fluids are delivered in a predetermined sequence by exerting positive pressure on said separate non-fluidly connected chambers, whereby said fluids are expressed from said chambers in said predetermined sequence.

3. The method of claim 2, wherein said positive pressure is created by compression of said separate non-fluidly connected chambers in a predetermined sequence.

4. The method of claim 1, wherein said plurality of fluids are delivered in a predetermined sequence by exerting negative pressure on said separate non-fluidly connected chambers, whereby said fluids are extracted from said chambers in said predetermined sequence.

5. The method of claim 4, wherein said negative pressure is created by pumping said fluids from said separate non-fluidly connected chambers in a predetermined sequence.

6. The method of claim 5, wherein said plurality of fluids flow from said separate non-fluidly connected chambers to a manifold comprising a separate input port in fluid communication with each said separate non-fluidly connected chamber and at least one common port, whereby said fluids flow through their respective input port to said common port in said predetermined sequence, and wherein said negative pressure is created downstream from said common port.

7. The method of claim 5, wherein negative pressure is exerted on each said separate non-fluidly connected chamber by a separate pump.

8. The method of claim 7, wherein each said separate pump is controlled by a programmable interface.

9. The method of claim 1, wherein said plurality of fluids are delivered in a predetermined sequence by gravity feed from said separate non-fluidly connected chambers, whereby said fluids flow from said chambers in said predetermined sequence.

10. The method of claim 9, wherein said plurality of fluids are delivered in a predetermined sequence by a differential hydrostatic head height in two or more separate non-fluidly connected chambers.

11. The method of claim 1, wherein said plurality of fluids flow from said separate non-fluidly connected chambers to a manifold comprising a separate input port in fluid communication with each said separate non-fluidly connected chamber and at least one common port, whereby said fluids flow to said common port in said predetermined sequence.

12. The method of claim 1, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by valves.

13. The method of claim 12, wherein said valve(s) are independently selected from the group consisting of umbrella valves, disc valves, poppet valves, duckbill valves, ball valves, flapper valves, shuttle valves, gate valves, slit membranes, and check valves.

14. The method of claim 1, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by an active control device.

15. The method of claim 14, wherein said active control device is selected from the group consisting of a stopcock, a pinch clamp, a pneumatically controlled valve, a vacuum controlled valve, a mechanically controlled valve, a hydraulically controlled valve, and an electrically controlled valve.

16. The method of claim 1, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by a passive control device.

17. The method of claim 1, wherein two or more chambers in said integral container become fluidly connected prior to or during delivery of said plurality of fluids, whereby a single chamber is formed.

18. A fluid delivery device, comprising:

an integral container comprising a plurality of fluids contained within separate non-fluidly connected chambers;

wherein said fluid delivery device is configured and arranged to deliver said plurality of fluids from said separate non-fluidly connected chambers to said at least one common port in a predetermined sequence.

19. The fluid delivery device of claim 18, further comprising a manifold comprising a separate input port in fluid communication with each said separate non-fluidly connected chamber and at least one common port.

20. The fluid delivery device of claim 18, further comprising one or more pumping elements.

21. The fluid delivery device of claim 20, wherein said one or more pumping elements exert positive pressure on said separate non-fluidly connected chambers.

22. The fluid delivery device of claim 21, wherein said positive pressure compresses said separate non-fluidly connected chambers in a predetermined sequence.

23. The fluid delivery device of claim 20, wherein said one or more pumping elements exert negative pressure on said separate non-fluidly connected chambers.

24. The fluid delivery device of claim 23, wherein said negative pressure pumps said fluids from said separate non-fluidly connected chambers in a predetermined sequence.

25. The fluid delivery device of claim 24, wherein said one or more pumping elements are downstream from said manifold common port.

26. The fluid delivery device of claim 24, wherein negative pressure is exerted on each said separate non-fluidly connected chamber by a separate pumping element.

27. The fluid delivery device of claim 18, wherein two or more separate non-fluidly connected chambers comprise different hydrostatic head heights.

28. The fluid delivery device of claim 18, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by valves.

29. The fluid delivery device of claim 28, wherein said valve(s) are independently selected from the group consisting of umbrella valves, disc valves, poppet valves, duckbill valves, ball valves, flapper valves, shuttle valves, gate valves, slit membranes, and check valves.

30. The fluid delivery device of claim 18, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by an active control device.

31. The fluid delivery device of claim 30, wherein said active control device is selected from the group consisting of a stopcock, a pinch clamp, a pneumatically controlled valve, a vacuum controlled valve, a mechanically controlled valve, a hydraulically controlled valve, and an electrically controlled valve.

32. The fluid delivery device of claim 18, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by a passive control device.

33. The fluid delivery device of claim 18, wherein two or more chambers in said integral container become fluidly connected prior to or during delivery of said plurality of fluids, whereby a single chamber is formed.

34. The fluid delivery device of claim 20, wherein said one or more pumping elements are controlled by a programmable interface.