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Method for labeling and fragmenting DNA

  • US 20030143555A1
  • Filed: 05/03/2002
  • Published: 07/31/2003
  • Est. Priority Date: 05/04/2001
  • Status: Active Grant
First Claim
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1. A method for labeling and fragmenting a single- or double-stranded deoxyribonucleic acid (DNA) comprising the following steps:

  • fragmenting the DNA by creating at least one abasic site on said DNA, attaching a marker to at least one of the fragments by means of a labeling reagent, said reagent covalently and predominantly coupling to at least one phosphate of said fragment.

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