Enzymatic-electrochemical measuring device
First Claim
1. Enzymatic-electrochemical measuring device based on a Clark electrode consisting of an Ag/AgCl reference electrode as anode and an electrochemically active working electrode, said electrodes being configured from a layer of electrolyte, a hydrophobic membrane and an enzyme as a sensor, characterized by at least two of the sensors being arranged as dual sensors, the electrodes of both sensors are covered by an electrolyte layer and a membrane with hydrophobic properties, the hydrophobic membrane is a predominantly gas permeable polymer, on which, in the case polymer, on which, in the case of working electrode, an enzyme is immobilized, whereas the hydrophobic membrane of the other sensor is devoid of enzymes.
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Abstract
The invention relates to an enzymatic-electrochemical measuring device, based on a Clark electrode, comprising an Ag/AgCl reference electrode as the anode and an electrochemically active working electrode, said electrodes being configured from a layer of electrolyte, a hydrophobic membrane and an enzyme as a sensor. The invention is characterised in that at least two of the sensors are arranged as dual sensors, the electrodes of both sensors are wetted in a uniform manner and covered by a layer of electrolyte and a membrane with hydrophobic properties, the hydrophobic membrane is a predominantly gas-permeable polymer, on which, in the case of the working electrode, an enzyme is immobilised, whereas the hydrophobic membrane of the other sensor is devoid of enzymes. The measuring device which can be commercially produced and is easy to use is used for determining, controlling and monitoring the presence and concentration of different analytes in medical diagnostics and in the food and biotechnological industries. The measuring device is particularly advantageous for determining the level of urinary glucose both in a stationary and an ambulant environment and can also he used by the elderly in their homes.
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10 Claims
- 1. Enzymatic-electrochemical measuring device based on a Clark electrode consisting of an Ag/AgCl reference electrode as anode and an electrochemically active working electrode, said electrodes being configured from a layer of electrolyte, a hydrophobic membrane and an enzyme as a sensor, characterized by at least two of the sensors being arranged as dual sensors, the electrodes of both sensors are covered by an electrolyte layer and a membrane with hydrophobic properties, the hydrophobic membrane is a predominantly gas permeable polymer, on which, in the case polymer, on which, in the case of working electrode, an enzyme is immobilized, whereas the hydrophobic membrane of the other sensor is devoid of enzymes.
Specification