Use of chemical sensor
First Claim
1. A chemical sensor (1) for selectively detecting an analyte in a solution, said sensor comprising a selective membrane (3), transducer means (4), an inlet (5) for a liquid flow, and an outlet (6), characterised in means (8) for injecting a recognition element into said flow, and a space provided between the transducer means (4) and the selective membrane (3), the transducer means (4) and the membrane (3) forming a flow-through chamber (2), one side of said membrane (3) being in contact with said solution containing said analyte, the analyte passing through the membrane (3) and interacting with the recognition element, said transducer means (4) converting the interaction into a signal (F) proportional to the concentration of the analyte in said solution.
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Abstract
A chemical sensor (1) for selectively detecting an analyte in a solution as described. The sensor comprises a flow-through chamber (2), a selective membrane (3), a transducer means (4), an inlet (5) for a liquid flow containing a recognition element, and an outlet (6). There is also described a method of selectively detecting an analyte in a solution, wherein a recognition element is contacted with the solution containing the analyte via a selective membrane, said contact resulting in a response detectable by transducer means. The recognition element is injected into a flow, the flow is passed into a flow-through chamber comprising a transducer means and the selective membrane, where it is contacted with the analyte passing from the solution outside the selective membrane, whereby the recognition element and the analyte interact to provide a signal which is detected by the transducer means. The use of the chemical sensor for detecting of analyte(s) in a reactor system, a flow system or in an in vivo system is also described.
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Citations
25 Claims
- 1. A chemical sensor (1) for selectively detecting an analyte in a solution, said sensor comprising a selective membrane (3), transducer means (4), an inlet (5) for a liquid flow, and an outlet (6), characterised in means (8) for injecting a recognition element into said flow, and a space provided between the transducer means (4) and the selective membrane (3), the transducer means (4) and the membrane (3) forming a flow-through chamber (2), one side of said membrane (3) being in contact with said solution containing said analyte, the analyte passing through the membrane (3) and interacting with the recognition element, said transducer means (4) converting the interaction into a signal (F) proportional to the concentration of the analyte in said solution.
- 8. A method of selectively detecting an analyte in a solution, wherein a recognition element is contacted with the solution containing the analyte via a selective membrane, said contact resulting in a response detectable by transducer means, characterised in that the recognition element is injected into a flow, the flow is passed into a flow-through chamber comprising the transducer means and the selective membrane, where it is contacted with the analyte passing from the solution out-side the selective membrane, whereby the recognition element and the analyte interacts to provide a signal which is detected by the transducer means.
Specification