Multi-layer dressing as medical drug delivery system
First Claim
25. The method of manufacturing a dressing, comprising the steps of:
- a. mixing the components of the surface-contacting layer together to form a standardized aerated mixture;
b. spreading the aerated mixture onto a smooth support to form a sheet of predetermined thickness;
c. mixing the components of said drug containing layer to form a standardized aerated mixture; and
d. spreading the aerated mixture of step c) on top of the mixure of step b) before the mixture of step b) is fully cured, and allowing both layers to cure simultaneously.
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Accused Products
Abstract
A medicated multi-layered polyurethane foam dressing and drug delivery device with cooling properties, used in body cavities and on damaged tissues, particularly bums. The dressing may have at least one therapeutic agent dispersed into the polyurethane layers; an optional outer layer of either a hydrogel formulated from a polyurethane or an adhesive elastomeric material; an optional drug-free fluid-retaining layer and/or a drug-reservoir layer, each comprised of hydrophilic polyurethane foam; a non-adherent, drug-loaded surface-contacting layer of a polyurethane hydrogel; and an optional cover sheet, for surface dressings. An interposed liquid transfer control may be used at a layer interface. The conformable dressing shapes include cylindrical, oval, flatsheets in pre-determined sizes; and may be secured with a secondary dressing. The contact surface may be channeled to enhance fluid distribution.
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Citations
33 Claims
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25. The method of manufacturing a dressing, comprising the steps of:
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a. mixing the components of the surface-contacting layer together to form a standardized aerated mixture;
b. spreading the aerated mixture onto a smooth support to form a sheet of predetermined thickness;
c. mixing the components of said drug containing layer to form a standardized aerated mixture; and
d. spreading the aerated mixture of step c) on top of the mixure of step b) before the mixture of step b) is fully cured, and allowing both layers to cure simultaneously. - View Dependent Claims (26, 27, 28, 29, 30)
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31. A method for manufacturing a dressing, comprising:
- the steps of;
a. mixing the components of said surface-contacting layer together to form a standardized aerated mixture;
b. spreading the aerated mixture of step a) onto a smooth support to form a sheet of pre-determined thickness, and allowing the sheet to fully cure;
c. mixing the components of said drug reservoir layer to form a standardized aerated mixture;
d. spreading the aerated mixture of step c) onto a smooth support to form a sheet of pre-determined thickness, and allowing the sheet to fully cure; and
e. sealing the sheet obtained in step b) to the sheet obtained in step d). - View Dependent Claims (32)
- the steps of;
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33-1. A method of delivering a drug selected from a predetermined group to an internal area of damaged tissue of a patient, consisting of the step of applying a dressing as set forth in claim 1 to said area.
Specification