Methods for monitoring analyte concentration using minimally invasive devices

• US 20030158472A1
• Filed: 03/03/2003
• Published: 08/21/2003
• Est. Priority Date: 05/25/2001
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Borzu Sohrab
• Inventors: Sohrab, Borzu
• Granted Patent: US 6,738,654 B2
• Time in Patent Office: Days
• US Class Current: 600/345
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/681 Wristwatch-type devices
• CPC Class Codes: G01N 33/50 Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing measuring or testing processes involving enzymes or microorganisms, compositions or test papers therefor; processes for forming such compositions, condition responsive control in microbiological or enzymological processes C12Q
• CPC Class Codes: G01N 33/66 involving blood sugars, e.g. galactose

Abstract

A method of monitoring the concentration of an analyte in a host or portion thereof over a given period of time. The method includes the steps of: (a) making a first analyte concentration measurement at a first point of time using a single use analyte concentration measuring device; (b) making a second analyte concentration measurement at a second point in time using a single use analyte concentration measuring device; and (c) making one or more additional analyte concentration measurements using another single use measuring device, wherein the analyte concentration measurements are made according to a selected schedule to monitor the concentration of analyte in a host over a given portion of time.

Claims

1. A method of monitoring the concentration of analyte in a host, said method comprising:

selecting a time period over which said analyte concentration is monitored;

selecting a scheduling mode for monitoring said analyte concentration over said time period;

making two or more analyte concentration measurements during said time period according to said scheduling mode, wherein said measurements are made automatically without human intervention;

modifying said scheduling mode based on results of said two or more analyte concentration measurements; and

making one or more additional analyte concentration measurements during said time period according to said modified scheduling mode, wherein said additional measurements are made automatically without human intervention.

2. The method of claim 1, wherein said scheduling mode comprises a measurement frequency.

3. The method of claim, 2 wherein said modifying said scheduling mode comprises increasing said measurement frequency.

4. The method of claim 1, wherein each of said measurements and said additional measurements are performed using a single use analyte concentration measurement means.

5. The method of claim 1, wherein said host comprises interstitial fluid.

6. The method of claim 1, wherein said measurements and said additional measurements are made in situ.

7. The method of claim 1, wherein said measurements and said additional measurements are made ex vivo.

8. The method of claim 1, wherein said method employs a device that comprises:

a plurality of measurement means; and

an activation means that activates each of said plurality of measurement means according to a predetermined schedule.

9. A method of monitoring the concentration of analyte in a host, said method comprising:

selecting a time period over which said analyte concentration is monitored;

selecting a scheduling mode for monitoring said analyte concentration over said time period;

making a plurality of analyte concentration measurements during said time period according to said scheduling mode, wherein said measurements are made automatically without human intervention; and

temporarily interrupting said scheduling mode to make an analyte concentration measurement during said time period, wherein said measurement is made with human intervention.