Novel human protease and polynucleotides encoding the same

• US 20030166902A1
• Filed: 02/19/2002
• Published: 09/04/2003
• Est. Priority Date: 02/20/2001
• Status: Abandoned Application

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Hu, Yi, Nepomnichy, Boris
• Application Number:
  US10/078,592
• Publication Number:
  US 20030166902A1
• Time in Patent Office: Days
• US Class Current: 536/23.2
• CPC Class Codes: A61P 19/02 for joint disorders, e.g. arthritis, arthrosis
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: A61P 35/00 Antineoplastic agents
• CPC Class Codes: C12N 9/6421 from mammals

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising at least 34 contiguous bases of nucleotide sequence from SEQ ID NO:

1.

3. An isolated nucleic acid molecule according to claim 1 wherein said nucleotide sequence is a cDNA sequence.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

2; and

(b) hybridizes under highly stringent conditions to the nucleotide sequence of SEQ ID NO;

1 or the complement thereof.

4. An isolated nucleic acid molecule encoding a protein having the protease activity of the protease of SEQ ID NO:

2, and that hybridizes to the nucleotide sequence of SEQ ID NO;

1 under highly stringent conditions.