Fluid handling methods and systems
First Claim
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1. A fluid handling system, comprising:
- at least one analytic or synthetic component;
at least one fluid flow regulator that effects and/or regulates fluid flow through at least one fluid conduit when the fluid conduit is at least in fluid communication with the fluid flow regulator and the analytic or synthetic component;
at least one weight scale that detects a weight of fluid disposed in at least one fluid container when the fluid container is in sensory communication with the weight scale; and
, at least one controller that is operably connected at least to the weight scale and to the fluid flow regulator, which controller is configured to control the fluid flow regulator at least in response to fluid weight data received from the weight scale.
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Abstract
The present invention provides fluid handling systems and related methods that include weight scales for detecting weights of fluids disposed in fluid containers. The fluid handling systems, which are typically highly automated, provide for substantially continuous performance of methods that include the use of these fluid handling systems. The invention also provides kits that include various system components.
58 Citations
65 Claims
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1. A fluid handling system, comprising:
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at least one analytic or synthetic component;
at least one fluid flow regulator that effects and/or regulates fluid flow through at least one fluid conduit when the fluid conduit is at least in fluid communication with the fluid flow regulator and the analytic or synthetic component;
at least one weight scale that detects a weight of fluid disposed in at least one fluid container when the fluid container is in sensory communication with the weight scale; and
,at least one controller that is operably connected at least to the weight scale and to the fluid flow regulator, which controller is configured to control the fluid flow regulator at least in response to fluid weight data received from the weight scale. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A liquid chromatography system, comprising:
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at least one source fluid container;
at least one waste fluid container;
at least one weight scale in sensory communication with one or more of the source or waste fluid containers;
at least one liquid chromatography column;
at least one source fluid conduit that fluidly connects the source fluid container to the liquid chromatography column;
at least one waste fluid conduit that fluidly connects the waste fluid container to the liquid chromatography column;
at least one fluid flow regulator operably connected to one or more of;
the source fluid container, the waste fluid container, the source fluid conduit, the waste fluid conduit, or the liquid chromatography column, which fluid flow regulator effects and/or regulates fluid flow through the source fluid conduit, the waste fluid conduit, and/or the liquid chromatography column; and
,at least one controller that is operably connected at least to the weight scale and to the fluid flow regulator, which controller controls the fluid flow regulator in response to fluid data received from the weight scale. - View Dependent Claims (21, 22, 23, 24)
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25. A method of handling fluid, the method comprising:
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providing a fluid handling system that comprises;
at least a first weight scale;
a plurality of fluid containers, wherein at least a first fluid container is in sensory communication with the first weight scale;
at least one analytic or synthetic component;
at least one fluid conduit that fluidly communicates at least with the first fluid container and with the analytic or synthetic component;
at least one fluid flow regulator that is operably connected to the fluid conduit, which fluid flow regulator effects and/or regulates fluid flow through the fluid conduit; and
at least one controller that is operably connected at least to the first weight scale and to the fluid flow regulator, which controller controls the fluid flow regulator in response to fluid weight data received from at least the first weight scale; and
,flowing at least one fluid to or from the first fluid container with the fluid flow regulator until a weight of the fluid in the first fluid container detected by the first weight scale is above or below a first selected amount, thereby handling the fluid. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64)
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65. A kit, comprising:
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at least one fluid handling system that comprises;
at least one analytic or synthetic component;
at least one fluid flow regulator that effects and/or regulates fluid flow through at least one fluid conduit when the fluid conduit is in fluid communication with the fluid flow regulator and the analytic or synthetic component;
at least one weight scale that detects a weight of fluid disposed in at least one fluid container when the fluid container is in sensory communication with the weight scale; and
at least one controller that is operably connected at least to the weight scale and to the fluid flow regulator, which controller is configured to control the fluid flow regulator at least in response to fluid weight data received from the weight scale; and
,at least one set of instructions that directs use of the fluid handling system.
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Specification