Cleaning kit for an infrared glucose measurement system

• US 20030176775A1
• Filed: 02/04/2003
• Published: 09/18/2003
• Est. Priority Date: 10/13/1998
• Status: Abandoned Application

• Current Assignee: Medoptix Incorporated
• Original Assignee: Medoptix Incorporated
• Inventors: Berman, Herbert L.
• Application Number:
  US10/358,880
• Publication Number:
  US 20030176775A1
• Time in Patent Office: Days
• US Class Current: 600/310
• CPC Class Codes: A61B 2562/245 Means for cleaning the sensor in-situ or during use, e.g. hygienic wipes
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations
• CPC Class Codes: G01N 21/15 Preventing contamination of the components of the optical system or obstruction of the light path
• CPC Class Codes: G01N 21/552 Attenuated total reflection

Abstract

This invention involves a non-invasive glucose measurement device for determining blood glucose levels in the human body using infrared spectroscopy. The device is typically used on a fingertip and compares two specific regions of a measured infrared spectrum to determine the blood glucose level of the user. The invention further provides a cleaning kit for cleaning the skin exterior prior to taking a glucose measurement. The kit typically includes a glucose solvent and a solvent for removing the glucose solvent. The solvents have IR spectra, which have no peaks between about 8.25 micrometers and about 8.75 micrometers and between about 9.50 micrometers and about 10.00 micrometers. The solvents may be provided on absorbent wipes, and the wipes or their packaging may have features that prevent more than a single use. Similarly, the wipes or their packaging may have special features requiring their presence in order to activate the device.

Claims

1. A disposable wipe comprising:

a first solvent capable of removing glucose from the stratum corneum, said solvent having an IR spectra without absorbance peaks between about 8.25 micrometers and about 8.75 micrometers and between about 9.50 micrometers and about 10.00 micrometers; and

a support, wherein the solvent is absorbed or impregnated in the support.

2. The disposable wipe of claim 1 further comprising a sealed package, the package housing the wipe therein and being openable.

3. The disposable wipe of claim 2 wherein the package comprises a foiled liner on its inner surface.

4. The disposable wipe of claim 2 wherein the package further comprises a barcode.

5. The disposable wipe of claim 2 wherein the package further comprises a magnetic material.

6. The disposable wipe of claim 1 wherein the wipe further comprises a detectable chemical component.

7. The disposable wipe of claim 1, wherein the support is selected from the group consisting of a fabric, a woven, a nonwoven, a cloth, a pad, a polymeric or fibrous mixture, and any combination thereof.

8. The disposable wipe of claim 1 wherein the wipe is configured for a single use.

9. The disposable wipe of claim 8 wherein the wipe is configured for a single use by further comprising an additional chemical to prevent more than a single use.

10. The disposable wipe of claim 8 wherein the wipe is configured for a single use by being adapted to dry out quickly after a single use.

34. An infrared glucose measurement system comprising:

a device for measuring the glucose concentration of the stratum corneum said device comprising an infrared source for emitting an IR beam into an ATR plate, the IR beam having components at least in the region of a referencing wavelength and a measuring wavelength, the ATR plate having a measurement surface for contact with a human skin surface and for directing the IR beam against the skin surface, and at least two IR sensors for simultaneously measuring absorbance of at least said referencing wavelength and said measuring wavelength; and

the disposable wipe of claim 1.

11. A single-use disposable wipe comprising:

a second solvent capable of removing a first solvent capable of removing glucose from the stratum corneum, said second solvent having an IR spectra without absorbance peaks between about 8.25. micrometers and about 8.75 micrometers and between about 9.50 micrometers and about 10.00 micrometers; and

a support, wherein the solvent is absorbed or impregnated in the support.

12. The disposable wipe of claim 11 further comprising a sealed package, the package housing the wipe therein and being openable.

13. The disposable wipe of claim 12 wherein the package comprises a foiled liner on its inner surface.

14. The disposable wipe of claim 12 wherein the package further comprises a barcode.

15. The disposable wipe of claim 12 wherein the package further comprises a magnetic material.

16. The disposable wipe of claim 11 wherein the wipe further comprises a detectable chemical component.

17. The disposable wipe of claim 11, wherein the support is selected from the group consisting of a fabric, a woven, a nonwoven, a cloth, a pad, a polymeric or fibrous mixture, and any combination thereof.

18. The disposable wipe of claim 11 wherein the wipe is configured for a single use.

19. The disposable wipe of claim 18 wherein the wipe is configured for a single use by further comprising an additional chemical to prevent more than a single use.

20. The disposable wipe of claim 18 wherein the wipe is configured for a single use by being adapted to evaporate quickly after a single use.

35. An infrared glucose measurement system comprising:

a device for measuring the glucose concentration of the stratum corneum said device comprising an infrared source for emitting an IR beam into an ATR plate, the IR beam having components at least in the region of a referencing wavelength and a measuring wavelength, the ATR plate having a measurement surface for contact with a human skin surface and for directing the IR beam against the skin surface, and at least two IR sensors for simultaneously measuring absorbance of at least said referencing wavelength and said measuring wavelength; and

the disposable wipe of claim 11.

21. A cleaning kit for an infrared glucose measurement system comprising:

at least a first solvent capable of removing glucose from the stratum corneum; and

at least a second solvent capable of removing the first solvent capable of removing glucose from the stratum corneum, each of said solvents having an IR spectra without absorbance peaks between about 8.25 micrometers and about 8.75 micrometers and between about 9.50 micrometers and about 10.00 micrometers.

22. The cleaning kit of claim 21 further comprising a support, wherein the support is selected from the group consisting of a fabric, a woven, a nonwoven, a cloth, a pad, a polymeric or fibrous mixture, and any combination thereof.

23. The cleaning kit of claim 22 wherein at least one of the first or second solvents is absorbed or impregnated in the support.

24. The cleaning kit of claim 22 wherein the first solvent is absorbed or impregnated into at least a first portion of the support and the second solvent is absorbed or impregnated into at least a second portion of the support, wherein the first and second portions of the support are different.

25. The cleaning kit of claim 22 wherein the first solvent is absorbed or impregnated in a first support, and wherein the second solvent is absorbed or impregnated in a second support, wherein the first and second supports are independently selected from the group consisting of a fabric, a woven, a nonwoven, a cloth, a pad, a polymeric or fibrous mixture, and any combination thereof.

26. The cleaning kit of claim 22 wherein the first solvent comprises a mixture of alcohol and water.

27. The cleaning kit of claim 26 wherein the mixture is a 50-50 mixture of isopropyl alcohol and water.

28. The cleaning kit of claim 26 wherein the mixture is a 20-80 mixture of isopropyl alcohol and water.

29. The cleaning kit of claim 26 wherein the mixture is a 30-70 mixture of isopropyl alcohol and water.

30. The cleaning kit of claim 22 wherein the second solvent comprises a mixture of alcohol and water.

31. The cleaning kit of claim 30 wherein the mixture is a 95-5 mixture of isopropyl alcohol and water.

32. The cleaning kit of claim 30 wherein the mixture is a 90-10 mixture of isopropyl alcohol and water.

33. An infrared glucose measurement system comprising:

a device for measuring the glucose concentration of the stratum corneum said device comprising an infrared source for emitting an IR beam into an ATR plate, the IR beam having components at least in the region of a referencing wavelength and a measuring wavelength, the ATR plate having a measurement surface for contact with a human skin surface and for directing the IR beam against the skin surface, and at least two IR sensors for simultaneously measuring absorbance of at least said referencing wavelength and said measuring wavelength; and

the cleaning kit of claim 22.