Assay apparatus

• US 20030180815A1
• Filed: 05/23/2003
• Published: 09/25/2003
• Est. Priority Date: 07/31/2000
• Status: Active Grant

• Current Assignee: Cambridge Life Sciences PLC
• Original Assignee: Cambridge Life Sciences PLC
• Inventors: Rawson, Keith, Long, Nicholas David, Pearson, Michael Thomas
• Granted Patent: US 7,132,078 B2
• Time in Patent Office: Days
• US Class Current: 435/7.9
• CPC Class Codes: G01N 33/54388 based on lateral flow
• CPC Class Codes: G01N 33/558 using diffusion or migration of antigen or antibody immunochromatographic test strips G01N33/54387

Abstract

Assay apparatus comprising: a moulded cartridge containing a lateral flow test strip which has a label pad containing an enzyme antibody or antigen conjugate having affinity for an analyte; a capture zone having a capture antibody or antigen having affinity for said analyte; a reagent storage blister; a means for removing sample and/or label pad from the lateral flow test strip; a meter in which the cartridge is inserted enabling the control for reagent release from the reagent storage blister and for the sample and/or label pad removal and a means of providing quantitative measurement of said analyte.

Claims

1-1. Apparatus according to claim 1, wherein said result provides a quantitative measurement of the amount of said analyte contained in said biological sample.

13. Apparatus according to claim 13, wherein said cartridge is insertable into a meter which contains said control means.

14. Apparatus according to claim 14, wherein said cartridge includes a sample insertion aperture which is normally closed by a movable door, said door being opened automatically to allow the insertion of a patient sample upon insertion of said disposable cartridge into said meter.

17. Apparatus substantially as hereinbefore described with reference to the accompanying drawings.

18. A method of conducting an assay using assay apparatus, the method being substantially as hereinbefore described.

19. A method of detecting the presence of a substance in a sample, the method being substantially as hereinbefore described