Medication capsule, syringe used with medication capsule & method of administrating medication

• US 20030187404A1
• Filed: 09/24/2002
• Published: 10/02/2003
• Est. Priority Date: 09/25/2001
• Status: Active Grant

• Current Assignee: Ottfried Waldenburg
• Original Assignee: Ottfried Waldenburg
• Inventors: Waldenburg, Ottfried
• Granted Patent: US 7,112,188 B2
• Time in Patent Office: Days
• US Class Current: 604/200
• CPC Class Codes: A61M 2005/31598 having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
• CPC Class Codes: A61M 5/285 with sealing means to be broken or opened
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3287 Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence

Abstract

A medical syringe employs a capsule containing multiple doses of medication within a sealed storage chamber formed between concentric inner and outer walls. The inner wall forms a cavity including a delivery chamber from which a single dose of medication is ejected. The syringe includes an ejection port, an axial moveable plunger extending into the cavity and delivery chamber, and a body with a compartment that holds the capsule. With the plunger in a first position, the capsule is closed. With the plunger in a second position, the delivery chamber is filled with a single dose of medication. With the plunger in a third position, the single dose of medication is ejected from the delivery chamber though the injection port.

Claims

1. The combination of

(a) a capsule made of material that is compatible with long term storage therein of medication and containing multiple doses of said medication, said capsule including a sealed wall portion, and

(b) a syringe including

a body member that holds the capsule,

a delivery chamber accessible to the medication in the capsule upon opening of said sealed wall portion upon assembly of the body member and capsule, and

a manual operable plunger member extending into the delivery chamber that is displaceable therein to draw into the delivery chamber said single dose upon displacement of the plunger member in one direction and to eject said single dose from the delivery chamber upon displacement of the plunger member in the opposite direction.

2. The combination recited in claim 1 where the capsule comprises a glass chamber holding Insulin.

3. The combination recited in claim 2 where the glass chamber has a substantially cylindrical configuration.

4. The combination recited in claim 3 where the plunger member is axially oriented along a longitudinal axis of the glass cylindrical chamber.

5. The combination recited in claim 1 where the plunger member is at a proximal end of the syringe and an ejection port is at a distal end of the syringe, said injection port including a detachable needle.

6. The combination recited in claim 1 including a dose meter manually setting the amount of medication delivery with each single dose injection.

7. The combination of

(a) a capsule made of an inert material and containing multiple doses of medication, and including a passageway therein and a sealed wall portion made of an inert, elastomeric material, and

(b) a syringe including

a body member that holds the capsule,

a delivery chamber at least partially disposed within the passageway of the capsule and accessible to the medication in the capsule upon opening the sealed wall portion, and

a manual operable plunger member extending into the delivery chamber and manually moveable within the delivery chamber to draw into the delivery chamber from the capsule said single dose upon displacement of the plunger member in a first direction and to eject said single dose from the delivery chamber upon displacement of the plunger member in a second direction.

8. The combination recited in claim 7 where said plunger member has a plunger seal thereon that contacts an inside wall of the delivery chamber to assist in creating at least a partial vacuum within the delivery chamber as the plunger member moves in said first direction, said medication in the capsule flowing into the delivery chamber in response to said vacuum upon displacement of the plunger member in said first direction a predetermined distance corresponding to said single dose of medication.

9. The combination recited in claim 7 where the capsule is replaceable, cylindrical, made of glass, and holds Insulin.

10. The combination recited in claim 9 where the plunger member is axially oriented along a longitudinal axis of the glass cylindrical capsule and said second direction is opposite said first direction.

11. The combination recited in claim 7 where the plunger member is at a proximal end of the syringe and an ejection port at a distal end of the syringe, said injection port including a detachable needle.

12. The combination recited in claim 11 including a two-component connector, said capsule having at or near a distal end one component two-component connector and the plunger member having at a distal end the other component of the two-component connector, said two components being connected upon displacement of the plunger member in said second direction.

13. The combination recited in claim 11 where the injection port includes a self-sealing seal that prevents medication in the capsule flowing into the injection port and the plunger member has at a distal end a needle element that pierces said self-sealing seal upon displacement of the plunger member in said second direction.

14. The combination recited in claim 7 including a dose meter manually setting the amount of medication delivery with each single dose injection.

15. The combination recited in claim 14 where

the body member has a generally cylindrical configuration, a longitudinal axis, and a threaded wall portion at or neat a proximal end of the body member, and

the dose meter includes

a threaded ring element mounted on the threaded wall portion of the body member for manually rotation to move either towards or away from the proximal end of the body member when rotated, the axial position of the ring element setting the dosage of medication to be delivered, and

an end cap member seated on the proximal end of the body member and mounted to be manually moveable axially along said longitudinal axis, said ring element acting as a stop to limit the axial movement of the end cap member,

said end cap member upon engagement with the ring element enabling the ring element to be manually rotated to change the dosage setting.

16. The combination recited in claim 15 where the plunger member is attached to the end cap member.

17. A medical syringe comprising

a body member including a capsule made of an inert material and containing multiple doses of medication, said capsule including a longitudinal passageway therein having an access opening at a proximal end and a sealed wall portion made of an inert, elastomeric material at a distal end,

a tubular delivery chamber at least partially disposed within the longitudinal passageway of the capsule and accessible to the medication in the capsule upon opening the sealed wall portion, and

a manual operable plunger member extending through the opening in the capsule into the tubular delivery chamber and manually axially moveable within the tubular delivery chamber to draw into the delivery chamber from the capsule said single dose upon displacement of the plunger member in a first direction and to eject said single dose from the delivery chamber upon displacement of the plunger member in a second direction opposite said first direction,

said plunger member having a plunger seal thereon that contacts an inside wall of the tubular delivery chamber to assist in creating at least a partial vacuum within the delivery chamber as the plunger member moves in said first direction, said medication in the capsule flowing into the delivery chamber in response to said vacuum upon displacement of the plunger member in said first direction a predetermined distance corresponding to said single dose of medication.

18. The combination recited in claim 17 where the capsule is replaceable, cylindrical, made of glass, and holds Insulin.

19. The combination recited in claim 17 where the plunger member is at a proximal end of the syringe and an ejection port at a distal end of the syringe, said injection port including a detachable needle.

20. The combination recited in claim 19 including a two-component connector, said capsule having at or near a distal end one component two-component connector and the plunger member having at a distal end the other component of the two-component connector, said two components being connected upon displacement of the plunger member in said second direction.

21. The combination recited in claim 19 where the injection port includes a self-sealing seal that prevents medication in the capsule flowing into the injection port and the plunger member has at a distal end a needle element that pierces said self-sealing seal upon displacement of the plunger member in said second direction.

22. A medical syringe for use with a capsule containing multiple doses of medication, said syringe including

a body member including a compartment that holds a capsule inserted therein containing multiple doses of medication,

said body member having an ejection port at a distal end of the syringe, a dose meter including axial displaceable control element mounted at a proximal end of the syringe to rotate, said compartment being between the distal and proximal ends, and

a delivery chamber in said body member that is interactive with a capsule containing multiple doses of medication in the compartment to draw into said delivery chamber from the capsule a single dose of medication upon axial displacement of the dose meter,

said dose meter being manually attachable and detachable to the body member, upon detachment of the dose meter, said compartment being exposed to allow a capsule to be inserted into or removed therefrom and, upon attachment of the dose meter, said compartment holding a capsule containing multiple doses of medication,

said dose meter upon rotation setting the dosage of medication deliverable though the injection port by axial displacement of the dose meter.

23. The medical syringe of claim 22 where

the body member has a generally cylindrical configuration, a longitudinal axis, and a threaded wall portion at or neat the proximal end, and

the dose meter includes

a threaded ring element mounted on the threaded wall portion for manually rotation to move either towards or away from the proximal end when rotated, the axial position of the ring element setting the dosage of medication to be delivered, and

an end cap member seated on the proximal end of the body member and mounted to be manually moveable axially along said longitudinal axis, said ring element acting as a stop to limit the axial movement of the end cap member,

said end cap member upon engagement with the ring element enabling the ring element to be manually rotated to change the dosage setting.

24. The medical syringe of claim 22 including a two-component connector, said capsule having at or near a distal end one component two-component connector and the dose meter includes a plunger member, said plunger member having at a distal end the other component of the two-component connector, said two components being connected upon movement of the dose meter from a first axial position to a second axial position and disconnected upon movement of the dose meter from the second position to the first position.

25. The combination recited in claim 22 where the injection port includes a self-sealing seal that prevents medication in the capsule flowing into the injection port and the dose meter includes a plunger member, said plunger member having at a distal end a needle element that pierces said self-sealing seal upon movement of the dose meter from a first axial position to a second axial position and disengages from the self-sealing seal upon movement of the dose meter from the second position to the first position.

26. The medical syringe of claim 22 where the delivery chamber includes a tubular element into which the plunger member extends, said opener member engaging the tubular element and having a seal fitting snug against the tubular element to grip said tubular element and, in response to movement of the plunger member, drawing medication from the capsule into the tubular element, said plunger member as it is moved from the second position towards the ejection port forcing medication in the tubular element out the injection port.

27. A, syringe comprising

a body member including an ejection port at a distal end and a plunger member at a proximal end and holding a capsule containing multiple doses of medication, said capsule having a cavity therein in which is seated a delivery chamber capable of holding a single dose of medication,

said plunger member having a segment extending into the cavity of the capsule and interactive with the delivery chamber, being axial moveable within the cavity between a closed position preventing medication from flowing from the capsule into the delivery chamber, a fill position where a single dose of medication from the capsule is drawn into the delivery chamber, and an ejection position where the single dose is injected from the delivery chamber through the injection port.

28. The syringe recited in claim 27 where the capsule comprises a glass chamber holding Insulin.

29. The syringe recited in claim 27 where delivery chamber is accessible to the medication in the capsule upon opening of a sealed wall portion to allow medication in the capsule to flow into the delivery chamber in response to a vacuum being created in the delivery chamber and where at least a partial vacuum is created in the delivery chamber upon movement of the plunger member into the fill position in a first direction a predetermined distance corresponding to said single dose of medication.

30. The syringe recited in claim 27 where said capsule has at or near a distal end one component a two-component connector and the plunger member has at a distal end the other component of the two-component connector, said two components being connected upon movement of the plunger member in the ejection position.

31. The syringe recited in claim 27 where the injection port includes a self-sealing seal that prevents medication in the capsule flowing into the injection port and the plunger member has at a distal end a needle element that pierces said self-sealing seal upon movement of the plunger member in the ejection position.

32. A medical syringe comprising

an ejection port at a distal end of the syringe,

a body member including a compartment that holds a capsule including a sealed storage chamber containing multiple doses of medication and having concentric outer and inner wall members and a seal at or near a distal end of the storage chamber that upon being opened provides access to the medication in the storage chamber,

said storage chamber being formed between said concentric wall members, with said inner wall member forming a cavity within the capsule accessible through an opening at a proximal end of the capsule, and

a delivery chamber in said cavity having opposed proximal and distal ends, said proximal end being accessible through the opening in the cavity and said distal end being accessible to the medication in the chamber upon opening of the seal in the chamber,

a plunger member at a proximal end of the syringe, said plunger member having a segment extending into the cavity of the capsule and into the delivery chamber and interactive therewith,

said plunger member being axial moveable within the delivery chamber between a closed position preventing medication from flowing from the capsule into the delivery chamber, a fill position where a single dose of medication from the capsule is drawn into the delivery chamber, and an ejection position where the single dose is injected from the delivery chamber through the injection port.

33. The syringe recited in claim 32 where the capsule comprises a glass chamber holding Insulin.

34. The syringe recited in claim 32 where the medication in the capsule flows into the delivery chamber in response to at least a vacuum being created in the delivery chamber and where at least a partial vacuum is created in the delivery chamber upon movement of the plunger member into the fill position in a first direction a predetermined distance corresponding to said single dose of medication.

35. The syringe recited in claim 32 includes a dose meter that sets the amount of medication delivered with each injection said single dosage of medication.

36. A medication capsule including

a closed, sealed, and sterile storage chamber holding multiple doses of medication and including a cavity, said storage chamber formed between an outer wall member and an inner wall member that are co-axial and concentric, with the inner wall member forming at least a portion of the cavity,

said storage chamber having a seal at the distal end and a proximal end that closes the storage chamber, said proximal end having an opening therein to provide access to the cavity.

37. A medication capsule including

a closed, sealed, and sterile storage chamber including a central cavity and made of inert material,

said storage chamber holding multiple doses of Insulin and formed between an outer cylindrical glass wall member and an inner cylindrical glass wall member that are co-axial and concentric, with the inner wall member forming at least a portion of the cavity,

said inner wall member having a first seal at a distal end that forms a bottom of the cavity and an opening at a proximal end to provide access to the cavity, and

said outer wall opposite the first seal being spaced from the first seal and having therein a second seal.

38. The inner wall member recited in claim 37 where the first and second seals are made of an inert, self-sealing elastomeric material.

39. A medication capsule including

a closed, sealed, and sterile storage chamber made of inert material and including a central longitudinal passageway extending through the capsule,

said storage chamber holding multiple doses of Insulin and formed between an outer cylindrical glass wall member and an inner cylindrical glass wall member that are co-axial and concentric, with the inner wall member having a tubular configuration with opposed open ends,

a seal at the distal end of the capsule between distal ends of the inner and outer cylindrical glass wall members.

40. The inner wall member recited in claim 39 where the seal is made of an inert, self-sealing elastomeric material.

41. A method of administering medication comprising

(a) providing a medication capsule including

a closed, sealed, and sterile storage chamber holding multiple doses of medication and including a cavity, said storage chamber formed between an outer wall member and an inner wall member that are co-axial and concentric, with the inner wall member forming at least a portion of the cavity,

said storage chamber having a seal at the distal end and a proximal end having an opening therein to provide access to the cavity,

(b) opening the seal to enable the release of individual single doses of medication from the sealed storage chamber of the capsule by placing said capsule in a compartment of a syringe having at a distal end an injection port including a detachable needle,

(c) inserting into the cavity a delivery chamber of the syringe, said syringe having a plunger member with a distal end in the delivery chamber and a proximal end extending outward from the cavity, said plunger member being axial moveable within the delivery chamber between a closed position preventing medication from flowing from the capsule into the delivery chamber, a fill position where a single dose of medication from the capsule is drawn into the delivery chamber, and an ejection position where the single dose is injected from the delivery chamber through the injection port,

(d) moving the plunger from the closed position to the fill position to fill the delivery chamber with a single dose of medication,

(e) sticking the detachable needle into a patient and then moving the plunger from the fill position to the ejection position to eject from the delivery chamber through the detachable needle the single dose in said delivery chamber into the patient and then withdrawing the needle from the patient,

(f) after withdrawing the needle from the patient, moving the plunger member from the ejection position into the closed position and detaching the needle from the syringe.

42. The method recited in claim 41 where the medication is Insulin.

43. A method of administering medication comprising

(a) providing a syringe with a detachable needle that is detached and replaced with each injection, said syringe including a medication capsule comprising a storage chamber holding multiple doses of medication and a delivery chamber interactive with a plunger member that when moved in a first direction draws a single dose of medication into the delivery chamber and when moved in a second direction injects medication from the chamber through the needle,

(b) with the delivery chamber holding a single dose of medication, sticking the needle into the patient and moving the plunger in the second direction to inject the single dose into the patient,

(c) removing the needle from the patient and detaching it from the syringe.

44. The method recited in claim 43 where the syringe is wiped with a disinfectant prior to attaching another needle to the syringe.

45. The method recited in claim 44 where the medication is Insulin.