Booster for therapy of diseases with ultrasound and pharmaceutical liquid composition containing the same
First Claim
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1. A booster for enhancing effects of ultrasound in the therapy of diseases, comprising:
- a. a medicament and b. microbubbles of a gas having a diameter of 0.1 to 100 μ
m in a liquid.
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Abstract
A booster comprising a plurality of microbubbles of a gas in a liquid, e.g. about 4×107 cells/ml of microbubbles of a gas having a diameter of 0.1 to 100 μm in a 3 to 5% human serum albumin solution, and a pharmaceutical liquid composition comprising the booster as set forth above and a medicament, which are useful for the therapy of various diseases together with exposure of ultrasonic, where the therapeutic effects of the medicament is enhanced by the application of ultrasound in the presence of the booster.
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Citations
12 Claims
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1. A booster for enhancing effects of ultrasound in the therapy of diseases, comprising:
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a. a medicament and b. microbubbles of a gas having a diameter of 0.1 to 100 μ
m in a liquid. - View Dependent Claims (2, 3)
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4. A pharmaceutical liquid composition for the therapy of diseases with application of ultrasound, comprising:
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a. microbubbles of a gas having a diameter of 0.1 to 100 μ
m andb. a medicament selected from the group consisting of thrombolytic agents, hormones, antibiotics and antineoplastic agents in a liquid. - View Dependent Claims (5, 6, 7, 8, 9, 10, 11, 12)
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Specification