Intravascular flow modifier and reinforcement device

• US 20030191521A1
• Filed: 04/09/2003
• Published: 10/09/2003
• Est. Priority Date: 07/24/1998
• Status: Active Grant

• Current Assignee: Andrew J. Denardo, David A. Ferrera, Lok A. Lei, Peter Wilson
• Original Assignee: Andrew J. Denardo, David A. Ferrera, Lok A. Lei, Peter Wilson
• Inventors: Wilson, Peter, Ferrera, David A., Lei, Lok A., Denardo, Andrew J.
• Granted Patent: US 6,913,618 B2
• Time in Patent Office: Days
• US Class Current: 623/1.15
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61F 2/012 Multiple filtering units
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0071 spherical
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 2250/0036 differing in thickness
• CPC Class Codes: A61F 2250/0037 differing in height or in length
• CPC Class Codes: B21F 45/008 of medical instruments, e.g. stents, corneal rings medical science A61

Abstract

An intravascular flow modifier and vascular reinforcement for treatment of aneurysms is formed of one or more loops of wire of resilient material formed into a series of transverse loops and longitudinal connecting sections to configure an essentially cylindrical reinforcement device that still allows, if desired, access to the neck of an aneurysm for insertion of embolic coils and the like. The proximal and distal regions of the sinusoidal loops may be more tightly coiled than the intermediate regions of the loops, or may have a larger diameter than the intermediate regions. The intravascular flow modifier and vascular reinforcement device can be provided with an outer covering that can be formed as a fiber, and can be woven, or can be formed as a ribbon wound about the intravascular flow modifier and vascular reinforcement device. The wire of resilient material can also be coated with a hydrophilic material. One or more round or oval intermediate loops extending radially outward may also be provided. An apparatus for removing clots may also be formed from one or more loops of wire of resilient material in a hollow conical shape non-detachably joined to a deployment device, to trap and hold clots within a vessel.

Claims

1. An intravascular flow modifier and vascular reinforcement device to be used in the intravascular treatment of blood vessels, comprising:

an elongate strand of resilient material having first and second proximal ends respectively connected by first and second legs of the elongate strand of resilient material to a distal middle loop of the elongate strand of resilient material, said first and second proximal ends being joined to a deployment device, said first and second legs of the elongate strand of resilient material forming a double strand of a plurality of sinusoidal loops having upper and lower arcs, said sinusoidal loops extending along a longitudinal axis intersecting said deployment device, said upper and lower arcs of said sinusoidal loops being curved about said longitudinal axis to form a hollow cylindrical circumferential pattern of loops about said longitudinal axis.

2. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein a plurality of said elongate strands are joined to said deployment device.

3. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein each of the first and second legs have proximal, intermediate and distal regions, said proximal and distal regions of said first and second legs of sinusoidal loops being more tightly coiled than said intermediate regions of said first and second legs of sinusoidal loops to thereby provide a greater contact surface area for anchoring of said proximal and distal regions within a vessel.

4. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein each of the first and second legs have proximal, intermediate and distal regions, said proximal and distal regions of said first and second legs of sinusoidal loops having a larger diameter than said intermediate regions of said first and second legs of sinusoidal loops to thereby provide a greater radial contact force for anchoring of said proximal and distal regions within a vessel.

5. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein each of the first and second legs have proximal, intermediate and distal regions, said intermediate regions of said first and second legs of sinusoidal loops having squared sinusoidal loops.

6. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein said elongate strand of resilient material is a stranded cable.

7. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein said elongate strand of resilient material is made of a superelastic material.

8. The intravascular flow modifier and vascular reinforcement device of claim 7, wherein said superelastic material is a nickel-titanium alloy.

9. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein said elongate strand of resilient material is made of a shape memory material.

10. The intravascular flow modifier and vascular reinforcement device of claim 9, wherein said shape memory material is a nickel titanium alloy.

11. The intravascular flow modifier and vascular reinforcement device of claim 9, wherein said shape memory material is a shape memory polymer.

12. The intravascular flow modifier and vascular reinforcement device of claim 1, further comprising an outer covering formed from a covering material selected from the group consisting of polyethylene terephthalate, polytetrafluoroethylene, polyamide, polyurethane, and liquid crystal polymer.

13. The intravascular flow modifier and vascular reinforcement device of claim 12, wherein said polyamide is a nylon.

14. The intravascular flow modifier and vascular reinforcement device of claim 12, wherein said covering material is woven.

15. The intravascular flow modifier and vascular reinforcement device of claim 12, wherein said covering material is formed as a fiber.

16. The intravascular flow modifier and vascular reinforcement device of claim 12, wherein said covering material is formed as a ribbon.

17. The intravascular flow modifier and vascular reinforcement device of claim 1, wherein the elongate strand of resilient material is coated with a hydrophilic material.

18. The apparatus of claim 1, said elongate strand of resilient material further comprising at least one intermediate loop between said first and second legs and said distal middle loop, said at least one intermediate loop extending radially outward from said longitudinal axis in said expanded configuration so as to allow said at least one intermediate loop to extend into an aneurysm extending from the vessel.

19. The apparatus of claim 18, wherein said at least one intermediate loop has a rounded configuration in said expanded configuration.

20. The apparatus of claim 18, wherein said at least one intermediate loop has an oval configuration in said expanded configuration.

21. An apparatus for removing clots from the vasculature of a patient, comprising:

an elongate strand of resilient material having first and second proximal ends respectively connected by first and second legs of the elongate strand of resilient material to a distal middle loop of the elongate strand of resilient material, said first and second proximal ends being non-detachably joined to a deployment device, said first and second legs of the elongate strand of resilient material forming a double strand of a plurality of sinusoidal loops having upper and lower arcs, said sinusoidal loops extending along a longitudinal axis intersecting said deployment device, said upper and lower arcs of said sinusoidal loops being curved about said longitudinal axis, said elongate strand of resilient material being movable from an initial compressed configuration to an expanded configuration extending outwardly from the longitudinal axis to trap and hold clots within a vessel, the elongate strand of resilient material being adapted to be placed within the vessel of the patient when the elongate strand of resilient material is in the compressed configuration and removed from the vessel when the elongate strand of resilient material is in the expanded configuration, whereby clots trapped by the loops can be withdrawn from the vessel.

22. The apparatus of claim 21, wherein said upper and lower arcs of said sinusoidal loops form a hollow conical circumferential pattern of loops about said longitudinal axis in said expanded configuration.