Systems and methods for locating and defining a target location within a human body
First Claim
1. A system for locating a target location within a human body, comprising:
- a first wireless implantable marker configured to be implanted within the human body at a location relative to the target location;
an instrument having a function-site and a first instrument marker connected to the instrument at a first predetermined site relative to the function-site;
a position detection system having a sensor that detects a position of the first wireless implantable marker relative to a reference location and a position of the first instrument marker relative to the reference location, wherein the position detecting system includes a computer that determines a relative position between the first wireless implantable marker and the first instrument marker based on the positions of the first wireless marker and the first instrument marker relative to the reference location; and
a user interface operatively coupled to the position detection system, the user interface having an indicator that denotes the position of the function-site of the instrument relative to the target location based on the relative position between the first wireless implantable marker and the first instrument marker.
1 Assignment
0 Petitions
Accused Products
Abstract
Systems and methods for locating and defining a target location within a human body. The system can include at least one marker, a probe, and a detector for use in locating the markers by providing information to a surgeon that is representative of changes in proximity between the probe and the marker. The marker can have various detection characteristics, e.g., gamma radiation, that are detectable by an associated probe and detector. The tissue volume is removed by manipulating a cutting tool based on the proximity information provided by the detector, which can be used by the surgeon to define the boundary of the tissue volume. The systems and methods of the invention are particularly useful in locating and then removing a tissue volume or other target location from amorphous, pliable tissue (e.g., breast tissue) or other body parts.
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Citations
86 Claims
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1. A system for locating a target location within a human body, comprising:
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a first wireless implantable marker configured to be implanted within the human body at a location relative to the target location;
an instrument having a function-site and a first instrument marker connected to the instrument at a first predetermined site relative to the function-site;
a position detection system having a sensor that detects a position of the first wireless implantable marker relative to a reference location and a position of the first instrument marker relative to the reference location, wherein the position detecting system includes a computer that determines a relative position between the first wireless implantable marker and the first instrument marker based on the positions of the first wireless marker and the first instrument marker relative to the reference location; and
a user interface operatively coupled to the position detection system, the user interface having an indicator that denotes the position of the function-site of the instrument relative to the target location based on the relative position between the first wireless implantable marker and the first instrument marker. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43)
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44. A system for locating a target location, comprising:
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a first wireless implantable marker configured to be implanted into a body at a location relative to the target location, wherein the first wireless marker emits a wireless signal; and
a position detection system having an energy source that emits an excitation energy and a sensor that detects a position of the first wireless implantable marker relative to a reference location. - View Dependent Claims (45, 46)
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47. A wireless marker for implantation, comprising:
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a biocompatible casing configured to be implanted into a human body relative to a target location within the human body;
a signal element in the casing, the signal element being configured to emit a response energy in reaction to an excitation energy; and
a fastener configured to hold the wireless marker at a reference location in a human body relative to the target location within the human body - View Dependent Claims (48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60)
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61. A wireless marker for implantation, comprising:
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a biocompatible casing configured to be implanted into a human body relative to a target location within the human body; and
an identifier on and/or in the casing that can be observed by an imaging system to distinguish the casing from other casings that have been implanted into the human body. - View Dependent Claims (62, 63, 64)
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65. A wireless marker for implantation, comprising:
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a biocompatible casing configured to be implanted into a human body relative to a target location within the human body; and
an identifier on and/or in the casing that can be observed visually to distinguish the casing from other casings that have been implanted into the human body. - View Dependent Claims (66, 67, 68, 69)
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70. An instrument for manipulation within a human, comprising:
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a handle;
a function-site coupled to the handle, the function-site being aligned with an alignment axis;
a first instrument marker along the alignment axis; and
a second instrument marker along the alignment axis.
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71. An instrument for manipulation within a human, comprising:
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a handle;
a function-site coupled to the handle, the function-site being aligned with an alignment axis; and
a first wireless instrument marker along the alignment axis, wherein the first wireless instrument marker emits a wireless signal that can be detected by a position detection system to determine a position of the first wireless instrument marker relative to a reference location.
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72. An instrument for manipulation within a human, comprising:
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a handle;
a function-site coupled to the handle, the function-site being aligned with an alignment axis;
a first wireless instrument marker along the alignment axis, wherein the first wireless instrument marker emits a wireless signal that can be detected by a position detection system to determine a position of the first wireless instrument marker relative to a reference location; and
a user interface attached to the instrument and coupled to the detection system, wherein the user interface includes an indicator of a relative position between the function-site and a target location within the human.
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73. A system for locating a target location within a human body, comprising:
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an instrument having a handle, a function-site coupled to the handle, and at least one instrument maker attached to the instrument at a predetermined location relative to the function-site; and
a detection system that detects a characteristic of the instrument marker and determines a configuration of the instrument and/or the function-site. - View Dependent Claims (74, 75)
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76. A method of providing information for a procedure in which a first wireless implantable marker is implanted in a human body relative to a target location and an instrument marker is coupled to an instrument at a predetermined site relative to a function-site on the instrument, the method comprising:
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emitting a resonating energy from the first wireless implanted marker;
sensing a location of the first wireless marker relative to a reference location;
sensing a location of the instrument marker relative to the reference location;
correlating a relative position between the first wireless marker and the instrument marker based on the sensed locations; and
determining a relative position between the function-site and the first wireless implanted marker by adding together the relative position between the first wireless marker and the target location, a relative position between the instrument marker and the function-site, and the relative position between the first wireless marker and the instrument marker. - View Dependent Claims (77, 78, 79)
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80. A method of treating a target location within a human body, comprising:
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exciting a wireless marker implanted in the body by emitting an excitation energy in a manner that causes the marker to emit a response energy;
sensing the response energy; and
determining a position of the wireless marker relative to a reference location based on the sensed response energy. - View Dependent Claims (81, 82, 83, 84, 85, 86)
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Specification