Arterial spin labeling using time varying gradients
First Claim
Patent Images
1. A method for conducting an MR fluid flow study, said method comprising:
- applying a first amplitude modulated magnetic field gradient to a predetermined volume of said fluid flowing into a region of interest;
applying a first amplitude modulated RF irradiation to the predetermined volume;
acquiring first data for at least a portion of the region of interest;
applying a second RF irradiation to the predetermined volume of said fluid;
acquiring second data for the at least a portion of the region of interest; and
generating compensated fluid flow data for the at least a portion of the region of interest, wherein the fluid flow data is a function of at least the first data and the second data.
2 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to a method and system for conducting a magnetic resonance fluid flow study by conducting a labeling procedure and a control procedure and combining datasets from those procedures to create a dataset for the fluid flow study. An amplitude modulated magnetic field gradient and amplitude modulated RF irradiation may be applied during a labeling procedure. Likewise, amplitude modulated RF irradiation may be applied during a control procedure. An amplitude modulated magnetic field gradient may also be applied during the control procedure.
21 Citations
50 Claims
-
1. A method for conducting an MR fluid flow study, said method comprising:
-
applying a first amplitude modulated magnetic field gradient to a predetermined volume of said fluid flowing into a region of interest;
applying a first amplitude modulated RF irradiation to the predetermined volume;
acquiring first data for at least a portion of the region of interest;
applying a second RF irradiation to the predetermined volume of said fluid;
acquiring second data for the at least a portion of the region of interest; and
generating compensated fluid flow data for the at least a portion of the region of interest, wherein the fluid flow data is a function of at least the first data and the second data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
-
-
25. A method for compensating for at least the magnetization transfer effects, comprising the following steps:
-
applying an amplitude modulated magnetic field gradient;
applying an amplitude modulated control RF irradiation, wherein an envelope for the amplitude modulation of the control RF irradiation is similar to an envelope for the amplitude modulation of the magnetic field gradient;
applying an amplitude modulated labeling RF irradiation. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
-
-
37. An MR apparatus constructed and arranged to perform fluid flow imaging, said scanner comprising:
-
a module for generating amplitude modulated labeling RF irradiation; and
a module for generating an amplitude modulated magnetic field gradient wherein the amplitude modulation of the magnetic field gradient is similar to amplitude modulation of the labeling RF irradiation. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46, 47)
-
-
48. A computer readable medium encoding instructions that, when executed, direct a method for generating an image of fluid flow obtained from an MR system, said method comprising:
-
generating a label image from an MR data obtained by spin labeling flowing fluid using an amplitude modulated labeling RF irradiation and amplitude-modulated magnetic field gradient;
generating a control image from an MR data obtained by simulating at least magnetization transfer effects using amplitude modulated control RF irradiation and an amplitude modulated magnetic field gradient; and
generating the image of the fluid flow by subtracting the label image from the control image. - View Dependent Claims (49, 50)
-
Specification