Device for withdrawing or administrating a substance and method of a device

• US 20030195474A1
• Filed: 05/23/2003
• Published: 10/16/2003
• Est. Priority Date: 06/08/2000
• Status: Active Grant

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Martin, Frank E., Pettis, Ronald J., Harvey, Noel G., Lastovich, Alexander G., Down, James
• Granted Patent: US 8,172,815 B2
• Time in Patent Office: Days
• US Class Current: 604/187
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2037/003 having a lumen
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: B33Y 80/00 Products made by additive manufacturing

Abstract

A device includes a plurality of skin penetrating devices for delivering or withdrawing a substance through the skin of a patient. The device has a support formed with a top and bottom end and a plurality of channels extending axially through the support. A plurality of the skin penetrating members is positioned in the channels with a tip extending from the bottom end of the support. A coupling member is attached to the support for coupling with a fluid supply and directing the fluid to the skin penetrating members. The skin penetrating members have a length of about 100 microns to about 2000 microns and are about 30 to 50 gauge.

Claims

1. A device for withdrawing or delivering a substance through the skin of a patient, said device comprising:

a support having an axial dimension with a top end and a bottom end and a plurality of spaced-apart axial channels extending from said top end to said bottom end; and

a skin penetrating member positioned in each of said channels, each of said skin penetrating members having a first end coupled to said housing and a second end extending axially from said bottom end of said support.

2. The device of claim 1, wherein said skin penetrating member has an exposed end extending from said bottom end of said housing a length of about 1 micron to about 500 microns.

3. The device of claim 2, wherein said exposed end of said skin penetrating member has a length of about 500 microns to about 1000 microns.

4. The device of claim 1, further comprising a coupling member coupled to said top end of said support and having a cavity for forming a fluid flow path to said channels, said coupling member having a coupling for coupling with a collecting reservoir or a fluid supply.

5. The device of claim 1, wherein said skin penetrating member is a hollow cannula for withdrawing or delivering a substance through the skin of a patient.

6. The device of claim 1, wherein said skin penetrating members are solid and said support includes a fluid passage to said skin penetrating member.

7. The device of claim 6, wherein said device is a sampling device and said device comprises a fluid retaining member.

8. The device of claim 1, wherein said first end of said skin penetrating members are substantially flush with said top end of said support.

9. The device of claim 1, wherein said first end of said skin penetrating members are recessed in said channel and spaced from said top end of said housing.

10. The device of claim 1, wherein said skin penetrating members are cannulas of about 31 to about 34 gauge.

11. The device of claim 1, wherein said skin penetrating members have an exposed length extending from said bottom of at least 500 microns.

12. A method of forming a device for penetrating the skin of a patient comprising the steps of:

providing a support having a top end and a bottom end; and

providing a plurality of skin penetrating members having a first end and a second end and coupling said first end of skin penetrating members to said support with said second end being spaced from said bottom end of said support.

13. The method of claim 12, wherein said support includes a plurality of spaced apart channels, said method comprising positioning said skin penetrating members in said channels.

14. The method of claim 13, wherein said channels extend between said top end and said bottom end and said method comprises positioning said skin penetrating members in said channels in said support where said first end of said skin penetrating member is substantially flush with said top end.

15. The method of claim 14, comprising positioning said skin penetrating members in said channels in said support where said first end is spaced from said top end and is recessed in said channels.

16. The method of claim 13, comprising positioning said skin penetrating members in said channels where said second end is spaced from said bottom end a distance of about 10 microns to about 500 microns.

17. The method of claim 13, comprising bonding said skin penetrating members to said support with an adhesive.

18. The method of claim 13, comprising bonding said skin penetrating members by thermal welding or sonic welding.

19. The method of claim 13, wherein said skin penetrating members are coupled to said support by a friction fit.

20. The method of claim 13, wherein said support has a base extending axially from said bottom end, said method comprising placing said base against a planar member, positioning said skin penetrating members in said channels whereby said second ends of said cannulas contact said planar member, coupling said skin penetrating members to said support, and separating said base from said support.

21. The method of claim 20, wherein said base is an annular collar.

22. The method of claim 13, comprising the step of arranging said skin penetrating members in an array and molding said support around said array to couple said skin penetrating members to said support.