Moisturizing skin gel and method

• US 20030198616A1
• Filed: 04/23/2002
• Published: 10/23/2003
• Est. Priority Date: 04/23/2002
• Status: Abandoned Application

• Current Assignee: Combe Incorporated
• Original Assignee: Combe Incorporated
• Inventors: Howard, John R.
• Application Number:
  US10/127,588
• Publication Number:
  US 20030198616A1
• Time in Patent Office: Days
• US Class Current: 424/70.13
• CPC Class Codes: A61K 2800/5422 nonionic
• CPC Class Codes: A61K 31/4152 having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
• CPC Class Codes: A61K 8/345 containing more than one hydroxy group
• CPC Class Codes: A61K 8/731 Cellulose; Quaternized cellulose derivatives
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin

Abstract

A skin moisturizing composition comprising water, a skin moisturizer, a water soluble hydroxyalkylcellulose polymer and additives is free of fats and oils. The composition derives substantial water-barrier properties from the water soluble hydroxyalkylcellulose polymer.

Claims

1. An aqueous skin moisturizing composition having substantial water-barrier properties comprising a water soluble hydroxyalkylcellulose polymer, a skin moisturizer and water, and being free of a film-forming polyglyceryl methacrylate polymer, occlusive fats or oils.

2. The composition of claim 1, wherein said composition is in the form of a gel.

3. The composition of claim 1, wherein said water soluble hydroxyalkylcellulose polymer is hydroxyethylcellulose.

4. The composition of claim 1, wherein said skin moisturizer is an alkylenepolyol.

5. The composition of claim 4 wherein said alkylenepolyol is glycerin.

6. The composition of claim 1, further comprising an agent selected from the group consisting of vulnerary agents, antihistamines, emulsifiers, antipruritics, antimicrobial, antibacterial or antiseptic agents, stabilizers, preservatives, and mixtures thereof.

7. The composition of claim 6, comprising allantoin in an amount less than about 1.0 percent by weight of the composition.

8. The composition of claim 6, comprising diphenhydramine hydrochloride in an amount less than about 1.0 percent by weight of the composition.

9. The composition of claim 6, comprising dibucaine, or a cosmetically acceptable salt thereof, in an amount less than about 1.0 percent by weight of the composition.

10. The composition of claim 6, comprising isopropyl methyl phenol in an amount less than about 1.0 percent by weight of the composition.

11. An aqueous skin moisturizing composition according to claim 1, comprising:

about 80.0 to about 90.0 weight percent deionized water, about 1.0 to about 3.0 weight percent hydroxyethylcellulose, about 0.1 to about 3.0 weight percent pramoxine hydrochloride, about 0.01 to about 0.5 weight percent benzethonium chloride, about 8.0 to about 15.0 weight percent glycerin, about 0.01 to about 0.5 weight percent aloe powder, about 0.1 to about 4.0 weight percent of a dimethicone copolyol detackifier, and about 0.01 to about 2.0 weight percent preservative.

12. An aqueous skin moisturizing composition according to claim 1, comprising:

about 80.0 to about 90.0 weight percent deionized water, about 1.0 to about 3.0 weight percent hydroxyethylcellulose, about 8.0 to about 15.0 weight percent glycerin, about 0.1 to about 1.0 weight percent dibucaine hydrochloride, about 1.0 to about 3.0 weight percent diphenhydramine hydrochloride, about 0.01 to about 0.5 weight percent benzethonium chloride, about 0.1 to about 2.0 weight percent polysorbate 20, about 0.01 to about 0.5 weight percent isopropyl methyl phenol, and about 0.1 to about 0.5 weight percent allantoin.

13. An aqueous skin-care composition consisting essentially of:

about 70.0 to about 98.0 percent by weight water;

about 0.1 to about 4.0 percent by weight water soluble hydroxyalkylcellulose polymer;

about 1.0 to about 20.0 percent by weight glycerin;

about 0.1 to about 2.0 percent by weight of one or more vulnerary agents;

about 0.1 to about 4.0 percent by weight of one more antihistamines;

about 0.1 to about 1.0 percent by weight of one or more emulsifiers;

about 0.01 to about 1.0 percent by weight of one or more antimicrobials, antibacterials or antiseptics; and

about 0.1 to about 6.0 percent by weight of one or more antipruritics or anesthetics.

14. The composition of claim 13, including about 84.1 weight percent deionized water, about 2.0 weight percent hydroxyethylcellulose, about 10.0 weight percent of a 96 weight percent solution of glycerin, about 0.5 weight percent dibucaine hydrochloride, about 2.0 weight percent diphenhydramine hydrochloride, about 0.10 weight percent benzethonium chloride, about 1.0 percent polysorbate 20, about 0.10 weight percent isopropyl methyl phenol, and about 0.20 weight percent allantoin.

15. A method of reducing transepidermal water loss comprising the step of applying to the skin of a subject in need thereof an effective amount of an aqueous skin moisturizing composition comprising a water soluble hydroxyalkylcellulose polymer, a skin moisturizer and water, and free of film-forming polyglyceryl methacrylate polymer, occlusive fats or oils.

16. The method of claim 15, wherein said composition is a gel comprising about 1 to about 3 percent by weight hydroxyethylcellulose, about 80 to about 90 percent by weight deionized water, about 8 to about 12 percent by weight glycerin.

17. The method of claim 16, wherein said composition further comprises at least one additive selected from the group consisting of vulnerary agents, antipruritics, anesthetics, stabilizers, preservatives, antimicrobials, antibacterials, antiseptics, and emulsifiers.