Precise cardiac lead placement based on impedance measurements

• US 20030199938A1
• Filed: 04/22/2002
• Published: 10/23/2003
• Est. Priority Date: 04/22/2002
• Status: Abandoned Application

• Current Assignee: Chester Struble, Karel Smits
• Original Assignee: Chester Struble, Karel Smits
• Inventors: Smits, Karel, Struble, Chester
• Application Number:
  US10/127,034
• Publication Number:
  US 20030199938A1
• Time in Patent Office: Days
• US Class Current: 607/27
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 5/29 for permanent or long-term implantation
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61N 1/0573 chacterised by means penetrating the heart tissue, e.g. helix needle or hook
• CPC Class Codes: A61N 1/08 Arrangements or circuits for monitoring, protecting, controlling or indicating for external stimulators A61N1/3603; for implantable neurostimulators A61N1/36128; for heart stimulators A61N1/37; for defibrillators A61N1/3925
• CPC Class Codes: A61N 1/3625 External stimulators
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/37 Monitoring; Protecting
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators

Abstract

A method of implanting a medical lead includes measuring impedance associated with an electrode disposed on an implantable lead at a cardiac location, and positioning the electrode based on the measured impedance. The method may be used specifically for positioning a medical lead within the interventricular septum that separates the left and right ventricles of the heart. By using impedance as an indication of the positioning of the lead, the implantation process can be improved and simplified, and negative effects associated with piercing the left ventricular wall can be avoided.

Claims

1. A method of implanting a medical lead comprising:

measuring electrical impedance between an electrode disposed on an implantable lead and a reference potential as the electrode is positioned within cardiac tissue ; and

positioning the electrode at a location in the cardiac tissue based on the measured impedance.

2. The method of claim 1, wherein the electrode is a conical shaped electrode disposed at a distal end of the lead.

3. The method of claim 1, wherein measuring impedance comprises measuring resistance.

4. The method of claim 1, further comprising:

inserting the lead into an interventricular septum;

measuring impedance associated with an electrode disposed on a distal end of the lead within an interventricalar septum location; and

positioning the electrode within the interventricular septum based on the measured impedance.

5. The method of claim 4, further comprising positioning the electrode without puncturing a left ventricular wall.

6. The method of claim 4, further comprising positioning the electrode within a left ventricular endocardium based on the measured impedance.

7. The method of claim 1, wherein positioning the electrode based on the measured impedance further includes receiving an audible sound indicative of measured impedance and positioning the electrode based on the audible sound.

8. The method of claim 1, further comprising delivering an electrical signal at the cardiac location;

measuring impedance between the electrode disposed on an implantable lead and a reference electrode in response to the delivered signal; and

positioning the electrode based on the measured impedance.

9. The method of claim 8, further comprising:

inserting the lead into an interventricular septum;

delivering the electrical signal to the heart at an interventricular location associated with an electrode disposed on a distal end of the lead;

measuring impedance between the electrode disposed on a distal end of the lead and the reference electrode; and

positioning the electrode within the interventricular septum based on the measured impedance.

10. The method of claim 9, wherein inserting the lead into an interventricular septum comprises:

anchoring an outer lead to a right ventricular wall; and

inserting an inner lead into the interventricular septum.

11. The method of claim 10, wherein outer lead includes an outer lead electrode positioned adjacent a right ventricular wall upon anchoring an outer lead to a right ventricular wall.

12. The method of claim 11, wherein the outer lead electrode is the reference electrode.

13. The method of claim 11, wherein the outer lead electrode is a stimulation electrode for stimulating a right ventricle.

14. The method of claim 1, wherein the implantable lead includes non-continuous spiral anchoring features, and wherein positioning the electrode based on the measured impedance comprises screwing non-continuous anchoring features of the lead into the cardiac location.

15. The method of claim 14, wherein the non-continuous spiral anchoring features include fibrous growth holes.

16. The method of claim 1, wherein measuring impedance comprises measuring impedance between the electrode disposed on the implantable lead and a reference electrode disposed on a pacemaker.

17. The method of claim 1, wherein measuring impedance comprises measuring impedance between the electrode disposed on the implantable lead and a reference electrode in response to a stimulation pulse provided at the electrode disposed on the implantable lead.

18. The method of claim 1, wherein measuring impedance comprises measuring impedance between the electrode disposed on the implantable lead and a reference electrode in response to a high frequency lead integrity signal provided at the electrode on the implantable lead.

19. A system comprising:

an implantable lead including an electrode disposed on the lead; and

an implantation output device coupled to the lead that generates impedance measurements indicative of impedance between the electrode disposed on the lead and a reference electrode, and generates a lead location output signal based on the impedance measurements.

20. The system of claim 19, lead location output signal provides an indication of lead location within an interventricular septum.

21. The system of claim 19, wherein the implantation output device further includes a display, wherein lead location output signal provides visual output via the display indicative of lead location within an interventricular septum.

22. The system of claim 19, wherein the implantation output device further includes a speaker, wherein lead location output signal provides audio output via the speaker indicative of lead location within an interventricular septum.

23. An implantable medical lead comprising:

an outer lead including a proximal end, a distal end, and anchoring features disposed at the distal end, wherein the outer lead further includes a threaded channel; and

an inner lead including a proximal end, a distal end, and an electrode disposed at the distal end of the inner lead, wherein the inner lead includes spiral anchoring features that threadedly engage the threaded channel.

24. The implantable medical lead of claim 23, wherein the spiral anchoring features comprise non-continuous spiral anchoring features.

25. The implantable medical lead of claim 24, wherein the non-continuous spiral anchoring features include fibrous growth holes.

26. The implantable medical lead of claim 23, wherein the outer lead further includes an electrode disposed in close proximity to the distal end, wherein the anchoring features of the outer lead are disposed adjacent the electrode of the outer lead.

27. An implantable medical device comprising:

a medical lead including;

an outer lead including a proximal end, a distal end, and anchoring features disposed at the distal end, wherein the outer lead further includes a threaded channel; and

an inner lead including a proximal end, a distal end, and an electrode disposed at the distal end of the inner lead, wherein the inner lead includes spiral anchoring features that threadedly engage the threaded channel; and

a pacemaker coupled to the proximal ends.

28. The device of claim 27, wherein the pacemaker controls stimulation pulses delivered by at least one of the electrodes.

29. The device of claim 27, wherein the pacemaker processes signals detected by at least one of the electrodes.

30. The device of claim 27, wherein the spiral anchoring features comprise non-continuous spiral anchoring features.

31. The device of claim 30, wherein the non-continuous spiral anchoring features define fibrous growth holes.

32. The device of claim 27, wherein the outer lead further includes an electrode disposed in close proximity to the distal end, wherein the anchoring features of the outer lead are disposed adjacent the electrode of the outer lead.

33. A system comprising:

an implantable lead including an electrode; and

a lead location means coupled to the lead, for generating impedance measurements indicative of impedance between the electrode disposed on the lead and a reference electrode and generating a lead location output signal based on the received impedance measurements.

34. The system of claim 33, wherein the lead location output signal provides an indication of lead location within an interventricular septum.

35. The system of claim 33, wherein the implantation output device further includes a display, wherein lead location output signal provides visual output via the display indicative of lead location within an interventricular septum.

36. The system of claim 35, wherein the implantation output device further includes a speaker, wherein lead location output signal provides audio output via the speaker indicative of lead location within an interventricular septum.

37. An implantable medical lead comprising:

an outer lead including a proximal end, a distal end, and means for anchoring the outer lead on a right ventricular wall disposed at the distal end, wherein the outer lead further includes a threaded channel; and

an inner lead including a proximal end, a distal end, and an electrode disposed at the distal end of the inner lead, wherein the inner lead includes means for anchoring the inner lead into an interventricular septum, wherein the means for anchoring the inner lead threadedly engages the threaded channel.

38. The implantable medical lead of claim 37, wherein the means for anchoring the inner lead include non-continuous spiral anchoring features.

39. The implantable medical lead of claim 38, wherein the non-continuous spiral anchoring features include fibrous growth holes.

40. The implantable medical lead of claim 37, wherein the outer lead further includes an electrode disposed in close proximity to the distal end, wherein means for anchoring the outer lead is disposed adjacent the electrode of the outer lead.