Controlled release transdermal drug delivery
First Claim
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1. A device for controlling the release of a substance at a site of interest in a biological membrane comprising:
- a means of monitoring a physiological state at the site of interest; and
a means of releasing a variable amount of said substance to the site of interest;
said amount varying in response to the status of said monitored physiological state.
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Abstract
Provided herein is a device for controlling the release of a substance at a site of interest in a biological membrane comprising a means of monitoring a physiological state at the site of interest; and a means of releasing a variable amount of the substance to the site of interest where the amount varies in response to the status of the monitored physiological state. Also provided are methods of using the device.
43 Citations
47 Claims
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1. A device for controlling the release of a substance at a site of interest in a biological membrane comprising:
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a means of monitoring a physiological state at the site of interest; and
a means of releasing a variable amount of said substance to the site of interest;
said amount varying in response to the status of said monitored physiological state. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 45, 46, 47)
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24. A device for controlling the release of a substance at a site of interest on a biological membrane comprising:
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a means for ablating or altering said biological membrane at the site of interest;
a means of monitoring a physiological state at the site of interest;
a means of releasing a variable amount of said substance to the site of interest;
said amount varying in response to the status of said monitored physiological state; and
a means for housing said device. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44)
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Specification