Implantable textile prostheses having PTFE cold drawn yarns

• US 20030204235A1
• Filed: 04/25/2002
• Published: 10/30/2003
• Est. Priority Date: 04/25/2002
• Status: Active Grant

• Current Assignee: Lifeshield Sciences LLC (Acacia Research Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Hebert, Charles B., Edens, Wesley I.
• Granted Patent: US 7,105,021 B2
• Time in Patent Office: Days
• US Class Current: 623/1.5
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61L 27/16 obtained by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/34 Macromolecular materials
• CPC Class Codes: A61L 27/507 for artificial blood vessels apparatus for applying cells on a blood vessel prosthesis A61F2/062
• CPC Class Codes: A61L 31/04 Macromolecular materials
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: C08L 27/18 Homopolymers or copolymers or tetrafluoroethene

Abstract

The present invention provides an implantable prosthesis and more specifically, an implantable tubular textile prosthesis comprising a biocompatible fabric having inner and outer surfaces and first and second ends; the fabric having a textile construction comprising cold drawn PTFE yarns having a substantially uniform denier and high molecular orientation. Use of cold drawn PTFE yarns result in implantable prostheses that have excellent abrasion resistance, strength and lubricity properties. Useful textile constructions include weaves, knits, braids, filament windings, spun windings and combinations thereof. The prostheses of the present invention are lubricious and have characteristics that closely resemble the properties of a natural body lumen.

Claims

1. An implantable textile prosthesis comprising:

a hollow tubular textile construction of a biocompatible yarn, wherein said yarn comprises a cold drawn PTFE yarn having a substantially uniform denier and high molecular orientation fabric.

2. The prosthesis of claim 1, wherein said textile construction is selected from the group consisting of weaves, knits, braids, filament windings, spun windings and combinations thereof.

3. The prosthesis of claim 1, wherein said prosthesis is a tubular vascular or endovascular graft.

4. The prosthesis of claim 1, wherein said prosthesis further includes a coating.

5. The prosthesis of claim 1, wherein said prosthesis includes a radially deformable support component.

6. The prosthesis of claim 5, wherein said support component is a radially deformable stent.

7. The prosthesis of claim 1, wherein said yarn has a linear density of at least about 40 denier;

and

further wherein said yarn has a linear density of no more than about 400 denier.

8. The prosthesis of claim 1, wherein said yarn is twisted with at least about 1 twist per inch;

and

further wherein said yarn is twisted with no more than about 10 twists per inch

9. The prosthesis of claim 1, wherein said yarn includes an anti-static lubricant.

10. The prosthesis of claim 1, wherein said yarn is a room temperature, cold drawn yarn.

11. The prosthesis of claim 1, wherein said prosthesis is impregnated with a leak resistant material.

12. The prosthesis of claim 1, wherein said prosthesis includes an axial yarn to control longitudinal extension thereof.

13. A implantable braided textile prosthesis with enhanced lubricity, biocompatibility and chemical resistance properties comprising a braided, hollow, tubular shaped fabric comprising a cold drawn PTFE yarn having a substantially uniform linear density and a high molecular orientation.

14. A method for making a biocompatible tubular prosthesis comprising:

a) selecting a plurality of biocompatible polymeric filaments comprising cold drawn PTFE yarns having a substantially uniform linear density and a highly oriented molecular structure;

b) selecting a textile construction pattern for engaging said yarns; and

c) engaging said yarns in accordance with said textile construction pattern to form said tubular prosthesis.

15. The method of claim 14, wherein selecting said textile construction pattern is selected from the group consisting of weaves, knits, braids, filament windings, spun windings and combinations thereof.

16. An implantable textile fabric comprising:

a textile construction of an engaging biocompatible yarn, wherein said yarn comprises a cold drawn PTFE yarn having a substantially uniform denier and high molecular orientation fabric.