RNA interference mediated inhibition of hepatitis B virus (HBV) using short interfering nucleic acid (siNA)
First Claim
Patent Images
1. A short interfering nucleic acid (siNA) molecule that down-regulates expression of a HBV gene by RNA interference.
2 Assignments
0 Petitions
Accused Products
Abstract
The present invention concerns methods and reagents useful in modulating hepatitis B virus (HBV) gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to short interfering nucleic acid (siNA) or short interfering RNA (siRNA) molecules capable of mediating RNA interference (RNAi) against against hepatitis B virus (HBV).
409 Citations
31 Claims
- 1. A short interfering nucleic acid (siNA) molecule that down-regulates expression of a HBV gene by RNA interference.
-
2. A short interfering nucleic acid (siNA) molecule that inhibits HBV replication.
Specification