Method and apparatus for detecting acoustic oscillations in cardiac rhythm

• US 20030208240A1
• Filed: 05/03/2002
• Published: 11/06/2003
• Est. Priority Date: 05/03/2002
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Carlson, Gerrard M., Pastore, Joseph M., Zhu, Qingsheng, Ding, Jiang, Lincoln, William C.
• Granted Patent: US 7,113,825 B2
• Time in Patent Office: Days
• US Class Current: 607/17
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36842 Multi-site stimulation in the same chamber
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting

Abstract

A cardiac rhythm management device is configured to detect oscillations in cardiac rhythm by measuring the amplitudes of heart sounds during successive heart beats. Upon detection of acoustic alternans, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.

Claims

1. An implantable cardiac rhythm management device, comprising:

an accelerometer for generating a phonocardiogram signal;

a controller for processing the phonocardiogram signal to detect heart sounds within the phonocardiogram signal and to measure oscillations in the amplitudes of the heart sounds during successive heart beats; and

,

wherein the controller is programmed to detect acoustic alternans when the measured oscillations exceed a specified magnitude and to adjust the operating behavior of the device when acoustic alternans is detected.

2. The device of claim 1 wherein the controller is programmed to detect oscillations in the amplitude of the first heart sound S1 in order to detect acoustic alternans.

3. The device of claim 1 wherein the controller is programmed to detect oscillations in the amplitude of the second heart sound S2 in order to detect acoustic alternans.

4. The device of claim 1 further comprising:

a sensing/pacing channel; and

,

wherein the controller is programmed to deliver pacing therapy in accordance with a bradycardia mode, and further wherein the controller is programmed to decrease a programmed pacing rate when acoustic alternans is detected.

5. The device of claim 1 further comprising:

a sensing/pacing channel; and

,

wherein the controller is programmed to deliver anti-tachycardia pacing therapy when a measured heart rate exceeds a specified tachycardia threshold rate, and further wherein the controller is programmed to decrease the tachycardia threshold rate when acoustic alternans is detected.

6. The device of claim 1 further comprising:

a first ventricular pacing channel;

a second ventricular pacing channel; and

,

wherein the controller is programmed to deliver pacing therapy in accordance with a bradycardia mode, and further wherein the controller is programmed to initiate ventricular resynchronization pacing by delivering paces through both ventricular pacing channels when acoustic alternans is detected.

7. The device of claim 1 further comprising:

a first ventricular pacing channel;

a second ventricular pacing channel; and

,

wherein the controller is programmed to deliver ventricular resynchronization pacing by delivering paces through both ventricular channels, and further programmed to adjust a resynchronization operating parameter when acoustic alternans is detected.

8. The device of claim 7 wherein the resynchronization operating parameter adjusted by the controller is an atrio-ventricular interval.

9. The device of claim 7 wherein the resynchronization operating parameter adjusted by the controller is a biventricular delay interval.

10. The device of claim 1 further comprising:

a first atrial pacing channel;

a second atrial pacing channel; and

,

wherein the controller is programmed to deliver pacing therapy in accordance with a bradycardia mode, and further wherein the controller is programmed to initiate atrial resynchronization pacing by delivering paces through both atrial channels when acoustic alternans is detected.

11. A method for operating an implantable cardiac rhythm management device, comprising:

generating a phonocardiogram with an accelerometer;

processing the phonocardiogram signal to detect heart sounds within the phonocardiogram signal and to measure oscillations in the amplitudes of the heart sounds during successive heart beats; and

,

detecting acoustic alternans when the measured oscillations exceed a specified magnitude and adjusting the operating behavior of the device when acoustic alternans is detected.

12. The method of claim 11 further comprising detecting oscillations in the amplitude of the first heart sound S1 in order to detect acoustic alternans.

13. The method of claim 11 further comprising detecting oscillations in the amplitude of the second heart sound S2 in order to detect acoustic alternans.

14. The method of claim 11 further comprising delivering pacing therapy in accordance with a bradycardia mode and decreasing a programmed pacing rate when acoustic alternans is detected.

15. The method of claim 11 further comprising delivering anti-tachycardia pacing therapy when a measured heart rate exceeds a specified tachycardia threshold rate and decreasing the tachycardia threshold rate when acoustic alternans is detected.

16. The method of claim 11 further comprising initiating ventricular resynchronization pacing by delivering paces to both ventricles when acoustic alternans is detected.

17. The method of claim 11 further comprising delivering ventricular resynchronization pacing by delivering paces through both ventricular channels and adjusting a resynchronization operating parameter when acoustic alternans is detected.

18. The method of claim 17 wherein the adjusted resynchronization operating parameter is an atrio-ventricular interval.

19. The method of claim 17 wherein the adjusted resynchronization operating parameter is a biventricular delay interval.

20. The method of claim 11 further comprising initiating atrial resynchronization pacing by delivering paces through both atrial channels when acoustic alternans is detected.

21. The method of claim 11 further comprising initiating ventricular resynchronization pacing by delivering left-ventricular only pacing when acoustic alternans is detected.

22. The method of claim 11 further comprising initiating ventricular resynchronization pacing by delivering multi-site pacing to the left ventricle when acoustic alternans is detected.