Multipurpose host system for invasive cardiovascular diagnostic measurement acquisition and display

• US 20030216621A1
• Filed: 05/20/2002
• Published: 11/20/2003
• Est. Priority Date: 05/20/2002
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: JOMED NV
• Inventors: Alpert, Howard David, Hoseit, Paul Michael
• Granted Patent: US 7,134,994 B2
• Time in Patent Office: Days
• US Class Current: 600/300
• CPC Class Codes: A61B 2560/045 with a separable interface unit, e.g. for communication
• CPC Class Codes: A61B 5/0035 adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/027 using catheters
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/6851 Guide wires
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 5/72 Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 5/7435 Displaying user selection data, e.g. icons in a graphical user interface
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/468 allowing annotation or message recording
• CPC Class Codes: A61B 8/488 : involving Doppler signals
• CPC Class Codes: G16H 30/40 : for processing medical images, e.g. editing
• CPC Class Codes: G16H 40/63 : for local operation

Abstract

A multifunctional invasive cardiovascular diagnostic measurement host is disclosed that interfaces a variety of sensor devices, such as guide wire-mounted pressure sensors, flow sensors, temperature sensors, etc, and provides a multi-mode graphical user interface providing a plurality of displays in accordance with the various types of sensors and measurements rendered by the sensors.

Claims

1. A multipurpose host system for invasive cardiovascular diagnostic measurement acquisition and display, the system comprising:

an external input signal bus interface for receiving data arising from cardiovascular diagnostic measurement sensors;

a plurality of measurement processing components for receiving data of particular sensor types and rendering diagnostic measurement parameter values according to the received data; and

a multi-mode graphical user interface host comprising a set of diagnostic measurement user interfaces including display components corresponding to data output rendered by specified ones of the plurality of measurement processing components.

2. The multipurpose host system of claim 1 wherein the plurality of measurement processing components includes a blood pressure processing component and a blood velocity processing component.

3. The multipurpose host system of claim 2 wherein the plurality of measurement processing components includes a position sensor processing component.

4. The multipurpose host system of claim 2 further comprising a pressure measurement display interface and wherein a ratio of a first measured pressure and a second measured pressure is rendered by the pressure measurement display interface.

5. The multipurpose host system of claim 2 further comprising a pressure measurement display interface and wherein a pressure gradient between a first measured pressure and a second measured pressure is rendered by the pressure measurement display.

6. The multipurpose host system of claim 2 further comprising a flow measurement display interface and wherein a ratio of flow velocity under high flow conditions and low velocity conditions is rendered by the flow measurement display.

7. The multipurpose host system of claim 1 wherein the plurality of measurement processing components includes a temperature processing component and a position sensor processing component.

8. The multipurpose host system of claim 1 wherein the multi-mode graphical user interface host includes a first display interface mode wherein blood pressure measurements are displayed and a second display interface mode wherein blood flow measurements are displayed.

9. The multipurpose host system of claim 8 wherein the multi-mode graphical user interface host further includes a third display interface mode graphically depicting a combination of display elements including pressure measurement display elements from the first display interface mode and flow measurement display elements from the second display interface.

10. The multipurpose host system of claim 1 wherein the plurality of measurement processing components are instantiated from component objects.

11. A multi-mode graphical user interface for a multifunction invasive cardiovascular diagnostic measurement system capable of processing a plurality of physiological parameter measurement signals rendered by sensors mounted upon one or more flexible elongate members, the multi-mode graphical user interface comprising:

a first mode graphically displaying a set of first parameter values associated with measurement of a first parameter in a vessel;

a second mode graphically displaying a set of second parameter values associated with measurement of a second parameter in the vessel; and

a combination mode simultaneously displaying the first and second parameter values rendered by the first mode and the second mode.

12. The multi-mode graphical user interface of claim 11, wherein the first and second parameters are chosen from the group consisting of pressure, flow velocity, pH, vessel compliance, temperature, Coronary Flow Reserve, Fractional Flow Reserve, and appearance.

13. The multi-mode graphical user interface of claim 11, wherein the first and second parameters are measured with first and second sensors mounted on the flexible elongate member.

14. The multi-mode graphical user interface of claim 11, wherein the first and second parameters are measured with first and second sensors disposed on first and second flexible elongate members, respectively.

15. A cardiovascular diagnostic measurement and display system for determining severity of a vessel blockage, the system comprising:

an external input signal interface for receiving measurement data from diagnostic measurement sensors mounted upon one or more flexible elongate members;

a cardiovascular measurement data processing component including;

a first processing component executed to render a first output indicative of Fractional Flow Reserve based upon sensed blood pressure measurement input values received via the external signal input interface, and

a second processing component executed to render a second output indicative of Coronary Flow Reserve based upon sensed blood flow measurement input values received via the external signal input interface; and

an output component for rendering the first and second outputs in an observable manner.

16. The system of claim 15 further comprising a guide wire comprising multiple sensors, and wherein at least a signal indicative of a sensed pressure is provided by the guide wire to the data processing component via the external signal input interface.

17. The system of claim 16 wherein at least a signal indicative of blood flow is provided by the guide wire to the data processing component via the external signal input interface.

18. The system of claim 17 wherein the multiple sensors include a Doppler ultrasound blood flow sensor.

19. The system of claim 16 wherein the multiple sensors include a pressure sensor.

20. The system of claim 15, further comprising a first guide wire including a pressure sensor and a second guide wire including a flow sensor.

21. An apparatus for determining the functional significance of stenosis, the apparatus comprising:

at least one functional measurement guide wire; and

a data analysis system coupled to the at least one guide wire,

wherein the data analysis system is adapted to determine Fractional Flow Reserve and Coronary Flow Reserve based on measurements obtained with the at least one guide wire.

22. The apparatus of claim 21, wherein the at least one guide wire comprises multiple sensors coupled to the data analysis system.

23. The apparatus of claim 22, wherein the multiple sensors comprise a Doppler ultrasound flow sensor and a pressure sensor.

24. The apparatus of claim 21, wherein the at least one functional measurement guide wire comprises a first functional measurement guide wire and a second functional measurement guide wire.

25. The apparatus of claim 21, wherein the first guide wire comprises a Doppler ultrasound flow sensor coupled to the data analysis system, and the second guide wire comprises a pressure sensor coupled to the data analysis system.